RRD-251 hydrochloride

Modify Date: 2024-04-03 11:57:34

RRD-251 hydrochloride Structure
RRD-251 hydrochloride structure
Common Name RRD-251 hydrochloride
CAS Number 72214-67-6 Molecular Weight 271.59400
Density 1.47g/cm3 Boiling Point 345.3ºC at 760 mmHg
Molecular Formula C8H9Cl3N2S Melting Point N/A
MSDS Chinese USA Flash Point 162.6ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of RRD-251 hydrochloride


RRD-251 hydrochloride is a small molecule disruptor of Rb/Raf-1 interaction, potently and selectively disrupts the Rb/Raf-1 (IC50=77 nM) but not Rb/E2F, Rb/prohibitin, Rb/cyclin E, and Rb/HDAC binding.

 Names

Name (2,4-dichlorophenyl)methyl carbamimidothioate,hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.47g/cm3
Boiling Point 345.3ºC at 760 mmHg
Molecular Formula C8H9Cl3N2S
Molecular Weight 271.59400
Flash Point 162.6ºC
Exact Mass 269.95500
PSA 75.17000
LogP 4.72210
Index of Refraction 1.643

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261
RIDADR NONH for all modes of transport

 Synthetic Route

~98%

RRD-251 hydrochloride Structure

RRD-251 hydroch...

CAS#:72214-67-6

Literature: UNIVERSITY OF SOUTH FLORIDA Patent: WO2007/62222 A2, 2007 ; Location in patent: Page/Page column 47; 49; 70 ;

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

RRD-251 hydrochloride
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