5-(4-Bromophenyl)-1,3-oxazole

Modify Date: 2024-01-02 18:26:58

5-(4-Bromophenyl)-1,3-oxazole Structure
5-(4-Bromophenyl)-1,3-oxazole structure
Common Name 5-(4-Bromophenyl)-1,3-oxazole
CAS Number 72571-06-3 Molecular Weight 224.05400
Density 1.524g/cm3 Boiling Point 315.8ºC at 760 mmHg
Molecular Formula C9H6BrNO Melting Point 78-80ºC
MSDS N/A Flash Point 144.8ºC

 Names

Name 5-(4-Bromophenyl)oxazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.524g/cm3
Boiling Point 315.8ºC at 760 mmHg
Melting Point 78-80ºC
Molecular Formula C9H6BrNO
Molecular Weight 224.05400
Flash Point 144.8ºC
Exact Mass 222.96300
PSA 26.03000
LogP 3.10410
Index of Refraction 1.58

 MSDS

Name: 5-(4-Bromophenyl)-1 3-oxazole 97% Material Safety Data Sheet
Synonym:
CAS: 72571-06-3
Section 1 - Chemical Product MSDS Name:5-(4-Bromophenyl)-1 3-oxazole 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
72571-06-3 5-(4-Bromophenyl)-1,3-oxazole 97% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 72571-06-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: yellow
Odor: odorless - slight odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 78 - 80 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H6BrNO
Molecular Weight: 224

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide, bromine.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 72571-06-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
5-(4-Bromophenyl)-1,3-oxazole - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 72571-06-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 72571-06-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 72571-06-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi:Irritant;
Risk Phrases 36/37/38
Safety Phrases S26-S37/39
HS Code 2934999090

 Synthetic Route

~%

5-(4-Bromophenyl)-1,3-oxazole Structure

5-(4-Bromopheny...

CAS#:72571-06-3

Literature: Tetrahedron Letters, , vol. 50, # 26 p. 3273 - 3276

~88%

5-(4-Bromophenyl)-1,3-oxazole Structure

5-(4-Bromopheny...

CAS#:72571-06-3

Literature: Ding, Zhenhua; Yoshikai, Naohiko Organic Letters, 2010 , vol. 12, # 18 p. 4180 - 4183

~58%

5-(4-Bromophenyl)-1,3-oxazole Structure

5-(4-Bromopheny...

CAS#:72571-06-3

Literature: Morton-Norwich Products, Inc. Patent: US4171307 A1, 1979 ;

~19%

5-(4-Bromophenyl)-1,3-oxazole Structure

5-(4-Bromopheny...

CAS#:72571-06-3

Literature: SIGNAL PHARMACEUTICALS, LLC Patent: WO2008/51493 A2, 2008 ; Location in patent: Page/Page column 179 ;

~19%

5-(4-Bromophenyl)-1,3-oxazole Structure

5-(4-Bromopheny...

CAS#:72571-06-3

Literature: Mortensen, Deborah S.; Perrin-Ninkovic, Sophie M.; Harris, Roy; Lee, Branden G.S.; Shevlin, Graziella; Hickman, Matt; Khambatta, Gody; Bisonette, Rene R.; Fultz, Kimberly E.; Sankar, Sabita Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 22 p. 6793 - 6799

~48%

5-(4-Bromophenyl)-1,3-oxazole Structure

5-(4-Bromopheny...

CAS#:72571-06-3

Literature: LaMattina, John L. Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2261 - 2262

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5-(4-bromophenyl)-1,3-oxazole
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