neplanocin A

Modify Date: 2024-01-04 17:45:10

neplanocin A Structure
neplanocin A structure
Common Name neplanocin A
CAS Number 72877-50-0 Molecular Weight 263.253
Density 1.9±0.1 g/cm3 Boiling Point 632.6±65.0 °C at 760 mmHg
Molecular Formula C11H13N5O3 Melting Point N/A
MSDS N/A Flash Point 336.4±34.3 °C

 Use of neplanocin A


()-Neplanocin A potently and irreversibly inactivates SAH hydrolase .It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity.

 Names

Name (-)-Neplanocin A
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 632.6±65.0 °C at 760 mmHg
Molecular Formula C11H13N5O3
Molecular Weight 263.253
Flash Point 336.4±34.3 °C
Exact Mass 263.101837
PSA 130.31000
LogP -0.31
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.882

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY5976500
CHEMICAL NAME :
3-Cyclopentene-1,2-diol, 3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-, (1R,2S,3R,5R)-
CAS REGISTRY NUMBER :
72877-50-0
LAST UPDATED :
199312
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C11-H13-N5-O3
MOLECULAR WEIGHT :
263.29
WISWESSER LINE NOTATION :
T56 BN DN FN HNJ IZ D- CL5UTJ A1Q DQ EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - rabbit Kidney
DOSE/DURATION :
8400 ug/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 38,1771,1989

 Safety Information

HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Neoplanocin A
neplanocin A
(1S,2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol
3-Cyclopentene-1,2-diol, 5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)-, (1S,2R,5R)-
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