(Z)-Butylidenephthalide

Modify Date: 2024-02-14 09:25:05

(Z)-Butylidenephthalide Structure
(Z)-Butylidenephthalide structure
Common Name (Z)-Butylidenephthalide
CAS Number 72917-31-8 Molecular Weight 188.22
Density 1.2±0.1 g/cm3 Boiling Point 328.3±41.0 °C at 760 mmHg
Molecular Formula C12H12O2 Melting Point N/A
MSDS N/A Flash Point 135.7±25.0 °C

 Use of (Z)-Butylidenephthalide


(Z)-3-Butylidenephthalide is an antihyperglycemic agent by inhibiting the activity of intestinal and yeast R-glucosidases (IC50=2.35 mM; Ki=4.86 mM)[1].

 Names

Name 3-butylidene-(3Z)-1(3H)-Isobenzofuranone
Synonym More Synonyms

 (Z)-Butylidenephthalide Biological Activity

Description (Z)-3-Butylidenephthalide is an antihyperglycemic agent by inhibiting the activity of intestinal and yeast R-glucosidases (IC50=2.35 mM; Ki=4.86 mM)[1].
Related Catalog
References

[1]. Fernando Brindis, et al. (Z)-3-butylidenephthalide from Ligusticum porteri , an α-glucosidase inhibitor. J Nat Prod. 2011 Mar 25;74(3):314-20.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 328.3±41.0 °C at 760 mmHg
Molecular Formula C12H12O2
Molecular Weight 188.22
Flash Point 135.7±25.0 °C
Exact Mass 190.099380
PSA 26.30000
LogP 1.69
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.567

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

(Z)-Butylidenephthalide
1-Ethyl-1-methyl-1,1a-dihydrocyclopropa[c][2]benzofuran-3(3aH)-one
Cycloprop[c]isobenzofuran-3(3aH)-one, 1-ethyl-1,1a-dihydro-1-methyl-
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