Geldanamycin,18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-,(6S,15R)-

Modify Date: 2024-04-05 14:17:00

Geldanamycin,18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-,(6S,15R)- structure	Common Name	Geldanamycin,18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-,(6S,15R)-
	CAS Number	73341-73-8	Molecular Weight	560.67900
	Density	1.19g/cm3	Boiling Point	698.9ºC at 760 mmHg
	Molecular Formula	C₃₀H₄₄N₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	376.5ºC

Name	Geldanamycin, 18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-o-methyl-, (6S,15R)
Synonym	More Synonyms

Density	1.19g/cm3
Boiling Point	698.9ºC at 760 mmHg
Molecular Formula	C₃₀H₄₄N₂O₈
Molecular Weight	560.67900
Flash Point	376.5ºC
Exact Mass	560.31000
PSA	149.57000
LogP	5.81680
Index of Refraction	1.565

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OL9056000

CHEMICAL NAME :: Macbecin II

CAS REGISTRY NUMBER :: 73341-73-8

LAST UPDATED :: 198509

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C30-H44-N2-O8.H2-O

MOLECULAR WEIGHT :: 578.78

WISWESSER LINE NOTATION :: T6-19- A GMV IU KU OU&TJ AQ DQ I1 M1 NOVZ O1 Q1 RO1 SO1 U1 VO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 10 umol/L

REFERENCE :: PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 24,321,1983

Precursor 0
DownStream 1
CAS#:108-24-7 Ethanoic anhydride

macbecin II