Decanedioic acid-d16

Modify Date: 2024-01-11 10:35:45

Decanedioic acid-d16 Structure
Decanedioic acid-d16 structure
Common Name Decanedioic acid-d16
CAS Number 73351-71-0 Molecular Weight 218.34600
Density N/A Boiling Point 294.5ºC(lit.)
Molecular Formula C10H2D16O4 Melting Point 133-137ºC(lit.)
MSDS N/A Flash Point N/A

 Use of Decanedioic acid-d16


Decanedioic acid-d16 is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].

 Names

Name 1,10-decanedioic-d16 acid

 Decanedioic acid-d16 Biological Activity

Description Decanedioic acid-d16 is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Bertuzzi A, et al. Sebacic acid binding to human plasma albumin. Biochem Pharmacol. 1993 Feb 9;45(3):697-702.  

 Chemical & Physical Properties

Boiling Point 294.5ºC(lit.)
Melting Point 133-137ºC(lit.)
Molecular Formula C10H2D16O4
Molecular Weight 218.34600
Exact Mass 218.22100
PSA 74.60000
LogP 2.27640
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