4-Bromophenethylamine

Modify Date: 2024-01-04 16:28:27

4-Bromophenethylamine Structure
4-Bromophenethylamine structure
Common Name 4-Bromophenethylamine
CAS Number 73918-56-6 Molecular Weight 200.076
Density 1.4±0.1 g/cm3 Boiling Point 271.3±0.0 °C at 760 mmHg
Molecular Formula C8H10BrN Melting Point N/A
MSDS N/A Flash Point 113.1±20.4 °C
Symbol GHS05
GHS05
Signal Word Danger

 Use of 4-Bromophenethylamine


ZH8651 is an agonist of TAAR1 which can activate both Gs and Gq signal pathway. ZH8651 can used in study schizophrenia[1].

 Names

Name 4-Bromophenethylamine
Synonym More Synonyms

 4-Bromophenethylamine Biological Activity

Description ZH8651 is an agonist of TAAR1 which can activate both Gs and Gq signal pathway. ZH8651 can used in study schizophrenia[1].
Related Catalog
References

[1]. Shang P, et al. Structural and signaling mechanisms of TAAR1 enabled preferential agonist design. Cell. 2023 Nov 22;186(24):5347-5362.e24.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 271.3±0.0 °C at 760 mmHg
Molecular Formula C8H10BrN
Molecular Weight 200.076
Flash Point 113.1±20.4 °C
Exact Mass 198.999649
PSA 26.02000
LogP 2.23
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.576

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735
WGK Germany 3
Packaging Group III
Hazard Class 8.0
HS Code 2921499090

 Synthetic Route

~87%

4-Bromophenethylamine Structure

4-Bromophenethy...

CAS#:73918-56-6

Literature: Lu, Zhiyao; Williams, Travis J. Chemical Communications, 2014 , vol. 50, # 40 p. 5391 - 5393

~21%

4-Bromophenethylamine Structure

4-Bromophenethy...

CAS#:73918-56-6

Literature: Ankner, Tobias; Hilmersson, Goeran Tetrahedron Letters, 2007 , vol. 48, # 32 p. 5707 - 5710

~58%

4-Bromophenethylamine Structure

4-Bromophenethy...

CAS#:73918-56-6

Literature: Ankner, Tobias; Hilmersson, Goeran Tetrahedron Letters, 2007 , vol. 48, # 32 p. 5707 - 5710

~%

4-Bromophenethylamine Structure

4-Bromophenethy...

CAS#:73918-56-6

Literature: Bioorganic and Medicinal Chemistry, , vol. 11, # 10 p. 2293 - 2299

~%

4-Bromophenethylamine Structure

4-Bromophenethy...

CAS#:73918-56-6

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 29, p. 123 - 141

~%

4-Bromophenethylamine Structure

4-Bromophenethy...

CAS#:73918-56-6

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 29, p. 123 - 141

~%

4-Bromophenethylamine Structure

4-Bromophenethy...

CAS#:73918-56-6

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 29, p. 123 - 141

 Customs

HS Code 2921499090
Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles3

More Articles
A facile one-pot preparation of alkyl aminoaryl sulfides for the synthesis of GW7647 as an agonist of peroxisome proliferator-activated receptor alpha.

J. Org. Chem. 71 , 5781, (2006)

We have developed two simple and high yielding one-pot syntheses of alkyl aminoaryl sulfides containing a series of four-steps: in situ protection of the free amine by reaction with a Grignard reagent...

Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA.

Anal. Bioanal. Chem 397 , 665-75, (2010)

Based on the template of a recently introduced derivatization reagent for aldehydes, 4-(2-(trimethylammonio)ethoxy)benzeneaminium dibromide (4-APC), a new derivatization agent was designed with additi...

Formation of pyrazinoisoquinoline ring system by the tandem amidoalkylation and N-acyliminium ion cyclization: An efficient synthesis of Praziquantel. Kim JH, et al.

Tetrahedron 54(26) , 7395-7400, (1998)

 Synonyms

2-(4-bromophenyl)ethan-1-amine
Benzeneethanamine, 4-bromo-
EINECS 277-636-2
2-(4-Bromophenyl)ethanamine
4-Bromophenethylamine
MFCD00008189
2-(4-Bromophenyl)ethylamine
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