Isopropamide

Modify Date: 2024-01-18 11:27:26

Isopropamide Structure
Isopropamide structure
Common Name Isopropamide
CAS Number 7492-32-2 Molecular Weight 353.52100
Density N/A Boiling Point N/A
Molecular Formula C23H33N2O+ Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Isopropamide


Isopropamide (R5) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt.

 Names

Name (3-carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C23H33N2O+
Molecular Weight 353.52100
Exact Mass 353.25900
PSA 43.09000
LogP 4.81180

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BP0690000
CHEMICAL NAME :
Ammonium, (3-carbamoyl-3,3-diphenylpropyl)diisopropylmethyl-
CAS REGISTRY NUMBER :
7492-32-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C23-H33-N2-O
MOLECULAR WEIGHT :
353.58
WISWESSER LINE NOTATION :
ZVXR&R&2K1&Y1&1&Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1032 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,132,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
957 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,132,1970

 Synonyms

(3-Aminocarbonyl-3,3-diphenylpropyl)diisopropylmethylaminium
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