2-Chloro-1,1,1-Trimethoxyethane

Modify Date: 2024-01-09 18:35:36

2-Chloro-1,1,1-Trimethoxyethane Structure
2-Chloro-1,1,1-Trimethoxyethane structure
Common Name 2-Chloro-1,1,1-Trimethoxyethane
CAS Number 74974-54-2 Molecular Weight 154.592
Density 1.1±0.1 g/cm3 Boiling Point 143.2±35.0 °C at 760 mmHg
Molecular Formula C5H11ClO3 Melting Point N/A
MSDS Chinese USA Flash Point 40.8±26.0 °C
Symbol GHS02
GHS02
Signal Word Warning

 Names

Name 1,1,1-Trimethoxy-2-Chloroethane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 143.2±35.0 °C at 760 mmHg
Molecular Formula C5H11ClO3
Molecular Weight 154.592
Flash Point 40.8±26.0 °C
Exact Mass 154.039673
PSA 27.69000
LogP 1.84
Vapour Pressure 6.8±0.3 mmHg at 25°C
Index of Refraction 1.412

 Safety Information

Symbol GHS02
GHS02
Signal Word Warning
Hazard Statements H226
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic;
Risk Phrases R10
Safety Phrases S16-S45
RIDADR UN 1993 3/PG 3
WGK Germany 3
HS Code 2909199090

 Synthetic Route

~76%

2-Chloro-1,1,1-Trimethoxyethane Structure

2-Chloro-1,1,1-...

CAS#:74974-54-2

Literature: Degussa AG Patent: EP1371624 A1, 2003 ; Location in patent: Page 3 ;

~%

2-Chloro-1,1,1-Trimethoxyethane Structure

2-Chloro-1,1,1-...

CAS#:74974-54-2

Literature: Tetrahedron Letters, , vol. 54, # 19 p. 2366 - 2368

~64%

2-Chloro-1,1,1-Trimethoxyethane Structure

2-Chloro-1,1,1-...

CAS#:74974-54-2

Literature: Cowden; Wilson; Bishop; Cottrell; Davies; Dolling Tetrahedron Letters, 2000 , vol. 41, # 44 p. 8661 - 8664

 Customs

HS Code 2909199090
Summary 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles3

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CVT-4325: a potent fatty acid oxidation inhibitor with favorable oral bioavailability.

Bioorg. Med. Chem. Lett. 14 , 6017-6021, (2004)

New inhibitors of palmitoyl-CoA oxidation are based on the introduction of nitrogen heterocycles in the 'Western Portion' of the molecule. SAR studies led to the discovery of CVT-4325 (shown), a poten...

A new synthesis of 1, 2, 4-triazolin-5-ones: application to the convergent synthesis of an NK 1 antagonist. Cowden CJ, et al.

Tetrahedron Lett. 41(44) , 8661-64, (2000)

 Synonyms

2-Chloro-1,1,1-Trimethoxyethane
Ethane, 2-chloro-1,1,1-trimethoxy-
MFCD00216629
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