Tert-Butylthiol

Modify Date: 2024-01-03 00:38:22

Tert-Butylthiol Structure
Tert-Butylthiol structure
Common Name Tert-Butylthiol
CAS Number 75-66-1 Molecular Weight 90.187
Density 0.8±0.1 g/cm3 Boiling Point 67.0±8.0 °C at 760 mmHg
Molecular Formula C4H10S Melting Point -1.1 °C
MSDS Chinese USA Flash Point -24.4±0.0 °C
Symbol GHS02 GHS07 GHS09
GHS02, GHS07, GHS09
Signal Word Danger

 Names

Name 2-Methyl-2-Propanethiol
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 67.0±8.0 °C at 760 mmHg
Melting Point -1.1 °C
Molecular Formula C4H10S
Molecular Weight 90.187
Flash Point -24.4±0.0 °C
Exact Mass 90.050323
PSA 38.80000
LogP 1.95
Vapour density 3.1 (vs air)
Vapour Pressure 160.1±0.1 mmHg at 25°C
Index of Refraction 1.437
Stability Stable. Flammable - note low flashpoint. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ7660000
CHEMICAL NAME :
2-Propanethiol, 2-methyl-
CAS REGISTRY NUMBER :
75-66-1
BEILSTEIN REFERENCE NO. :
0505947
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C4-H10-S
MOLECULAR WEIGHT :
90.20
WISWESSER LINE NOTATION :
SHX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4729 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Behavioral - coma
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
22200 ppm/4H
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
590 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Behavioral - coma
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16500 ppm/4H
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
201 ppm/6H/2W-I
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in spleen weight
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555472 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - B0110 No. of Facilities: 321 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 4717 (estimated)

 Safety Information

Symbol GHS02 GHS07 GHS09
GHS02, GHS07, GHS09
Signal Word Danger
Hazard Statements H225-H317-H411
Precautionary Statements P210-P273-P280
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes F:Flammable;Xn:Harmful;
Risk Phrases R11;R36;R43;R65
Safety Phrases S3-S16-S26-S39-S38-S36/37
RIDADR UN 2347 3/PG 2
WGK Germany 3
RTECS TZ7660000
Packaging Group II
Hazard Class 3.1

 Synthetic Route

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 Synonyms

Tert-Butylthiol
2-Methyl-2-propanethiol
t-Butyl mercaptan
TERT-BUTANETHIOL
tertiary-Butyl mercaptan
2-Methylpropane-2-thiol
MFCD00004857
t-Butylmercaptan
tert-butyl thiol
1,1-Dimethylethanethiol
EINECS 200-890-2
t-butylthiol
2-Propanethiol, 2-methyl-
propane-2-thiol, 2-methyl-
tert.-Butanethiol
tert-Butyl Mercaptan
tert-Butylmercaptan
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