Butantrone

Modify Date: 2024-02-25 08:29:23

Butantrone Structure
Butantrone structure
Common Name Butantrone
CAS Number 75464-11-8 Molecular Weight 296.31700
Density 1.324g/cm3 Boiling Point 490.1ºC at 760 mmHg
Molecular Formula C18H16O4 Melting Point N/A
MSDS N/A Flash Point 264.3ºC

 Names

Name 10-butanoyl-1,8-dihydroxy-10H-anthracen-9-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.324g/cm3
Boiling Point 490.1ºC at 760 mmHg
Molecular Formula C18H16O4
Molecular Weight 296.31700
Flash Point 264.3ºC
Exact Mass 296.10500
PSA 74.60000
LogP 3.14330
Index of Refraction 1.641

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CB1500000
CHEMICAL NAME :
9(10H)-Anthracenone, 1,8-dihydroxy-10-(1-oxobutyl)-
CAS REGISTRY NUMBER :
75464-11-8
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C18-H16-O4
MOLECULAR WEIGHT :
296.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1579 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from small intestine Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
139 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from small intestine Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 59,180,1986

 Synthetic Route

~%

Butantrone Structure

Butantrone

CAS#:75464-11-8

Literature: Groupement d'Interet Economique dit: Centre International 'de Recherches Dermatologiques C.I.R.D. Patent: US4696941 A1, 1987 ;

 Precursor & DownStream

Precursor  2

DownStream  1

 Synonyms

10-butyryl-1,8-dihydroxy-9-anthron
Butantrona [Spanish]
Butantronum [Latin]
Dithranol,10-butyryl
1,8-dihydroxy-10-(1'-oxobutyl)-9(10H)-anthracenone
9(10H)-ANTHRACENONE,1,8-DIHYDROXY-10-(1-OXOBUTYL)
Butantrona
1,8-dihydroxy-10-butyrylanthrone
10-Butyryl dithranol
10-butyryl-1,8-dihydroxy-9(10H)-anthracenone
Butantrone