(E)-3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)-2-methyl-prop-2-en-1-one

Modify Date: 2024-04-03 18:34:07

(E)-3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)-2-methyl-prop-2-en-1-one structure	Common Name	(E)-3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)-2-methyl-prop-2-en-1-one
	CAS Number	76880-22-3	Molecular Weight	358.83700
	Density	1.279g/cm3	Boiling Point	492.8ºC at 760 mmHg
	Molecular Formula	C₂₀H₂₀ClFN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	251.8ºC

Name	(E)-3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)-2-methylprop-2-en-1-one
Synonym	More Synonyms

Density	1.279g/cm3
Boiling Point	492.8ºC at 760 mmHg
Molecular Formula	C₂₀H₂₀ClFN₂O
Molecular Weight	358.83700
Flash Point	251.8ºC
Exact Mass	358.12500
PSA	23.55000
LogP	4.39070
Index of Refraction	1.632

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UD5573000

CHEMICAL NAME :: 2-Propen-1-one, 3-(4-(2-chlorophenyl)-1-piperazinyl)-1-(4-fluoropheny l)-2-methyl-

CAS REGISTRY NUMBER :: 76880-22-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H20-Cl-F-N2-O

MOLECULAR WEIGHT :: 358.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 19,695,1980

1-(2-Chlorophen...

CAS#:39512-50-0

2-Hydroxymethyl...

CAS#:65201-51-6

(E)-3-[4-(2-chl...

CAS#:76880-22-3

Literature: Pratap, Ram; Gupta, R. C.; Srimal, R. C.; Anand, Nitya Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 8 p. 695 - 698

Precursor 2
CAS#:39512-50-0 1-(2-Chlorophen... CAS#:65201-51-6 2-Hydroxymethyl...
DownStream 0

2-Propen-1-one,3-(4-(2-chlorophenyl)-1-piperazinyl)-1-(4-fluorophenyl)-2-methyl

3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)-2-methylprop-2-en-1-one

3-(4-(2-Chlorophenyl)-1-piperazinyl)-1-(4-fluorophenyl)-2-methyl-2-propen-1-one

(E)-3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)-2-methyl-prop-2-en-1-one

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms