MEGX (hydrochloride)
Modify Date: 2024-01-24 16:41:37
MEGX (hydrochloride) structure
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Common Name | MEGX (hydrochloride) | ||
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| CAS Number | 7729-94-4 | Molecular Weight | 242.75 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H19ClN2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MEGX (hydrochloride)Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide has proven to be a highly sensitive indicator of hepatic dysfunction, especially in the field of liver transplantation[1][2]. |
| Name | N-(2,6-Dimethylphenyl)-N2-ethylglycinamide hydrochloride (1:1) |
|---|---|
| Synonym | More Synonyms |
| Description | Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide has proven to be a highly sensitive indicator of hepatic dysfunction, especially in the field of liver transplantation[1][2]. |
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| Related Catalog | |
| References |
| Molecular Formula | C12H19ClN2O |
|---|---|
| Molecular Weight | 242.75 |
| Exact Mass | 242.11900 |
| PSA | 44.62000 |
| LogP | 3.69380 |
|
~74%
MEGX (hydrochloride) CAS#:7729-94-4 |
| Literature: CORUS PHARMA Patent: WO2005/63777 A1, 2005 ; Location in patent: Page/Page column 44 ; |
| N-Ethylglycinhydrochlorid |
| ethyl glycine hydrochloric acid salt |
| Glycine,N-ethyl-,hydrochloride |
| N-(2,6-dimethylphenyl)-2-ethylaminoacetamide hydrochloride |
| N-Aethyl-glycin-(2,6-dimethyl-anilid),Hydrochlorid |
| N-desethyl-lidocaine |
| 2-(ethylamino)acetic acid hydrochloride |
| N-ethyl-glycine-(2,6-dimethyl-anilide),hydrochloride |
| monoethylglycine xylidide hydrochloride |
| N-ethyl glycine hydrochloride |
| N-Aethyl-glycin,Hydrochlorid |
| Lidocaine Impurity 1 |