N2-Ethylguanosine

Modify Date: 2024-07-21 14:03:13

N2-Ethylguanosine structure	Common Name	N2-Ethylguanosine
	CAS Number	77312-39-1	Molecular Weight	311.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₇N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N2-Ethylguanosine

N2-Ethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(ethylamino)-3H-purin-6-one
Synonym	More Synonyms

Description	N2-Ethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. [2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₂H₁₇N₅O₅
Molecular Weight	311.29
Exact Mass	311.12300
PSA	149.01000

Guanosine,N-ethyl

N2-Ethylguanosine

Use of N2-Ethylguanosine

Names

N2-Ethylguanosine Biological Activity

Chemical & Physical Properties

Synonyms