Maytansine, O3-acetyl-O3-de2-(acetylmethylamino)-1-oxopropyl-22-demethyl-

Modify Date: 2024-03-02 07:24:35

Maytansine, O3-acetyl-O3-de2-(acetylmethylamino)-1-oxopropyl-22-demethyl- structure	Common Name	Maytansine, O3-acetyl-O3-de2-(acetylmethylamino)-1-oxopropyl-22-demethyl-
	CAS Number	77353-67-4	Molecular Weight	593.06500
	Density	1.34g/cm3	Boiling Point	789ºC at 760 mmHg
	Molecular Formula	C₂₉H₃₇ClN₂O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	431ºC

Name	Antibiotic C 15003PND-1
Synonym	More Synonyms

Density	1.34g/cm3
Boiling Point	789ºC at 760 mmHg
Molecular Formula	C₂₉H₃₇ClN₂O₉
Molecular Weight	593.06500
Flash Point	431ºC
Exact Mass	592.21900
PSA	151.93000
LogP	3.38830
Index of Refraction	1.592

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OQ2290500

CHEMICAL NAME :: Maytansine, O(sup 3)-acetyl-O(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-22-demethyl-

CAS REGISTRY NUMBER :: 77353-67-4

LAST UPDATED :: 199207

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C29-H37-Cl-N2-O9

MOLECULAR WEIGHT :: 593.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #25898

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #80-118490

Maytansine,O(sup 3)-acetyl-O(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-22-demethyl