Corylifol C

Modify Date: 2024-01-04 11:45:30

Corylifol C Structure
Corylifol C structure
Common Name Corylifol C
CAS Number 775351-91-2 Molecular Weight 338.35
Density 1.4±0.1 g/cm3 Boiling Point 601.5±55.0 °C at 760 mmHg
Molecular Formula C20H18O5 Melting Point N/A
MSDS N/A Flash Point 218.9±25.0 °C

 Use of Corylifol C


Corylifol C is a potent protein kinase inhibitor with IC50 valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively[1].

 Names

Name Corylifol C
Synonym More Synonyms

 Corylifol C Biological Activity

Description Corylifol C is a potent protein kinase inhibitor with IC50 valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively[1].
Related Catalog
References

[1]. Limper C, et al. Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells. J Pharm Pharmacol. 2013 Sep;65(9):1393-408.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 601.5±55.0 °C at 760 mmHg
Molecular Formula C20H18O5
Molecular Weight 338.35
Flash Point 218.9±25.0 °C
Exact Mass 338.115417
PSA 90.90000
LogP 4.93
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.667
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi

 Synonyms

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-hydroxy-8-(3-methyl-2-buten-1-yl)-
2-(3,4-Dihydroxyphenyl)-7-hydroxy-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
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