AUDA-BE

Modify Date: 2024-01-11 18:34:14

AUDA-BE Structure
AUDA-BE structure
Common Name AUDA-BE
CAS Number 776300-37-9 Molecular Weight 448.692
Density N/A Boiling Point N/A
Molecular Formula C27H48N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AUDA-BE


The prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively; prevents LPS-induced mortality and preserved systolic blood pressure, reduces NO production in mice.

 Names

Name AUDA-BE

 AUDA-BE Biological Activity

Description The prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively; prevents LPS-induced mortality and preserved systolic blood pressure, reduces NO production in mice.
References References 1. Morisseau C, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608. 2. Schmelzer KR, et al. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9772-7. 3. Motoki A, et al. Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2128-34. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C27H48N2O3
Molecular Weight 448.692
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