2,3-Dichloropropene

Modify Date: 2024-01-02 18:21:57

2,3-Dichloropropene structure	Common Name	2,3-Dichloropropene
	CAS Number	78-88-6	Molecular Weight	110.97000
	Density	1.204 g/mL at 25 °C(lit.)	Boiling Point	94 °C(lit.)
	Molecular Formula	C₃H₄Cl₂	Melting Point	10°C
	MSDS	Chinese USA	Flash Point	50 °F
	Symbol	GHS02, GHS05, GHS07, GHS08	Signal Word	Danger

Name	2,3-Dichloro-1-propene
Synonym	More Synonyms

Density	1.204 g/mL at 25 °C(lit.)
Boiling Point	94 °C(lit.)
Melting Point	10°C
Molecular Formula	C₃H₄Cl₂
Molecular Weight	110.97000
Flash Point	50 °F
Exact Mass	109.96900
LogP	1.97770
Vapour density	3.8 (vs air)
Vapour Pressure	44 mm Hg ( 20 °C)
Index of Refraction	n20/D 1.461(lit.)
Water Solubility	<0.1 g/100 mL at 22 ºC

2,3-Dichloropropene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC8400000

CHEMICAL NAME :: Propene, 2,3-dichloro-

CAS REGISTRY NUMBER :: 78-88-6

BEILSTEIN REFERENCE NO. :: 1361491

LAST UPDATED :: 199806

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C3-H4-Cl2

MOLECULAR WEIGHT :: 110.97

WISWESSER LINE NOTATION :: G1YGU1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3100 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1580 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 300 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5383 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 7 No. of Employees: 302 (estimated) No. of Female Employees: 3 (estimated)

Symbol	GHS02, GHS05, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H225-H302-H312-H315-H318-H332-H335-H341-H412
Precautionary Statements	P210-P261-P273-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	F:Flammable
Risk Phrases	R11;R20/21/22;R37/38;R40;R41;R52/53
Safety Phrases	S9-S16-S23-S26-S36/37/39-S61
RIDADR	UN 2047 3/PG 2
WGK Germany	3
RTECS	UC8400000
Packaging Group	II
Hazard Class	3
HS Code	29032900

Precursor 10
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CAS#:109-86-4 2-methoxyethanol CAS#:33037-07-9 1-bromo-2,3-dic...
DownStream 10
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HS Code	29032900

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper desc...

Mutagenicity of chloroolefins in the Salmonella/mammalian microsome test. III. Metabolic activation of the allylic chloropropenes allyl chloride, 1,3-dichloropropene, 2,3-dichloro-1-propene, 1,2,3-trichloropropene, 1,1,2,3-tetrachloro-2-propene and hexachloropropene by S9 mix via two different metabolic pathways.

Mutat. Res. 170(1-2) , 1-9, (1986)

In the presence of S9 mix all allylic chloropropenes tested exert considerable indirect mutagenic activity which is most pronounced for 1,2,3-trichloropropene. Lower as well as higher chlorinated deri...

Evidence for a radical mechanism of the dechlorination of chlorinated propenes mediated by the tetrachloroethene reductive dehalogenase of Sulfurospirillum muftivorans.

Environ. Sci. Technol. 41(21) , 7370-5, (2007)

The reductive dehalogenation of chlorinated propenes was studied with the tetrachloroethene reductive dehalogenase purified from Sulfurospirillum multivorans to obtain indications for a radical mechan...

MFCD00000943

2,3-dichloroprop-1-ene

EINECS 201-153-8