MMPX
MMPX structure
|
Common Name | MMPX | ||
|---|---|---|---|---|
| CAS Number | 78033-08-6 | Molecular Weight | 266.29600 | |
| Density | 1.249g/cm3 | Boiling Point | 476.4ºC at 760 mmHg | |
| Molecular Formula | C12H18N4O3 | Melting Point | 189-190ºC | |
| MSDS | Chinese USA | Flash Point | 241.9ºC | |
Use of MMPXMMPX is a selective inhibitor of Ca2±calmodulin-dependent phosphodiesterase I (PDE1). |
| Name | 8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione |
|---|---|
| Synonym | More Synonyms |
| Density | 1.249g/cm3 |
|---|---|
| Boiling Point | 476.4ºC at 760 mmHg |
| Melting Point | 189-190ºC |
| Molecular Formula | C12H18N4O3 |
| Molecular Weight | 266.29600 |
| Flash Point | 241.9ºC |
| Exact Mass | 266.13800 |
| PSA | 81.91000 |
| LogP | 0.22570 |
| Index of Refraction | 1.554 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
|
~%
MMPX CAS#:78033-08-6 |
| Literature: European Journal of Medicinal Chemistry, , vol. 22, p. 243 - 250 |
|
~%
MMPX CAS#:78033-08-6 |
| Literature: European Journal of Medicinal Chemistry, , vol. 22, p. 243 - 250 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease.
Nat. Commun. 6 , 6965, (2015) 3',5'-cyclic adenosine monophosphate (cAMP) is an ubiquitous second messenger that regulates physiological functions by acting in distinct subcellular microdomains. Although several targeted cAMP bios... |
|
|
Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta.
Biochem. Pharmacol. 38 , 3331, (1989) In this study three forms of cyclic nucleotide phosphodiesterase (PDE) isolated from rabbit aorta were pharmacologically characterized, and the consequence of selective inhibition of calmodulin-stimul... |
|
|
Methylxanthine inhibitors of phosphodiesterases.
Meth. Enzymol. 159 , 489, (1988)
|
| Tocris-0552 |
| 8-Methoxymethyl-IBMX |
| 8-methoxymethyl-3-isobutyl-1-methylxanthine |
| 3-isobutyl-8-methoxymethyl-1-methylxanthine |
| MFCD00211081 |
| Lopac-M-2547 |