Lanosterin

Modify Date: 2024-01-02 16:09:10

Lanosterin Structure
Lanosterin structure
 Common Name Lanosterin
CAS Number 79-63-0 Molecular Weight 426.717
Density 1.0±0.1 g/cm3 Boiling Point 498.9±44.0 °C at 760 mmHg
Molecular Formula C30H50O Melting Point 137 °C
MSDS Chinese USA Flash Point 221.1±20.7 °C

 Use of Lanosterin


Lanosterol is a key triterpenoid intermediate in the biosynthesis of Cholesterol.

 Names

Name lanosterol
Synonym More Synonyms

 Lanosterin Biological Activity

Description Lanosterol is a key triterpenoid intermediate in the biosynthesis of Cholesterol.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Chen N, et al. Biosynthetic Mechanism of Lanosterol: Cyclization. Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8693-6.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 498.9±44.0 °C at 760 mmHg
Melting Point 137 °C
Molecular Formula C30H50O
Molecular Weight 426.717
Flash Point 221.1±20.7 °C
Exact Mass 426.386169
PSA 20.23000
LogP 11.00
Appearance of Characters powder | white
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.530
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OE3360000
CHEMICAL NAME :
Lanosta-8,24-dien-3-ol, (3-beta)-
CAS REGISTRY NUMBER :
79-63-0
BEILSTEIN REFERENCE NO. :
2226449
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C30-H50-O
MOLECULAR WEIGHT :
426.80

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
1819 ug/kg
SEX/DURATION :
female 13 week(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - abortion
REFERENCE :
ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 27,528,1992

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS OE3360000

 Synthetic Route

 Articles60

More Articles
The mannoprotein TIR3 (CAGL0C03872g) is required for sterol uptake in Candida glabrata.

Biochim. Biophys. Acta 1851(2) , 141-51, (2015)

Sterol uptake in the pathogenic fungus, Candida glabrata, occurs via the sterol transporter, CgAus1p. Azole inhibition of sterol biosynthesis can under certain circumstances be reversed by adding exog...

Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes.

Food Chem. Toxicol. 53 , 317-24, (2013)

Ganodermanondiol, a biologically active compound, was isolated from the Lingzhi mushroom (Ganoderma lucidum). The present study examined the protective effects of ganodermanondiol against tert-butyl h...

FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26p.

Nat. Commun. 6 , 8613, (2015)

FR171456 is a natural product with cholesterol-lowering properties in animal models, but its molecular target is unknown, which hinders further drug development. Here we show that FR171456 specificall...

 Synonyms

Lanosterol
Lanster
MFCD00021108
Lanosta-8,24-dien-3-β-ol
Lanosterin
Kriptosterol
DUSOGEL
botalanbase
(3β)-Lanosta-8,24-dien-3-ol
Criptosterol
Lanosta-8,24-dien-3-ol, (3β)-
CRYPTOSTEROL
Kryptosterol
EINECS 201-214-9
(3β,5α)-4,4,14-trimethyl-Cholesta-8,24-dien-3-ol
Lanosta-8,24-dien-3β-ol (8CI)
Cholesta-8,24-dien-3-ol, 4,4,14-trimethyl-, (3β,5α)-
Lanosta-8,24-dien-3β-ol
(3β,20R)-Lanosta-8,24-dien-3-ol
(3S,5R,10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-17-[(2R)-6-methyl-5-hepten-2-yl]-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
lanosta-8,24-dien-3-ol, (3β,20R)-
Kryp-tosterol
(3b)-Lanosta-8,24-dien-3-ol
ISOCHOLESTEROL
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Chemsrc provides Lanosterin(CAS#:79-63-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Lanosterin are included as well.>> amp version: Lanosterin

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