DM3

Modify Date: 2024-01-10 20:50:32

DM3 Structure
DM3 structure
Common Name DM3
CAS Number 796073-54-6 Molecular Weight 766.341
Density 1.3±0.1 g/cm3 Boiling Point 942.2±65.0 °C at 760 mmHg
Molecular Formula C37H52ClN3O10S Melting Point N/A
MSDS N/A Flash Point 523.6±34.3 °C

 Use of DM3


DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)[1].

 Names

Name DM3

 DM3 Biological Activity

Description DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Maytansinoids

References

[1]. Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8).

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 942.2±65.0 °C at 760 mmHg
Molecular Formula C37H52ClN3O10S
Molecular Weight 766.341
Flash Point 523.6±34.3 °C
Exact Mass 765.306213
LogP 5.37
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.592