SirReal1

Modify Date: 2024-10-03 09:27:06

SirReal1 Structure
SirReal1 structure
Common Name SirReal1
CAS Number 801227-82-7 Molecular Weight 370.492
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H18N4OS2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SirReal1


A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM; displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

 Names

Name N-(5-Benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetamide
Synonym More Synonyms

 SirReal1 Biological Activity

Description A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM; displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).
References References 1. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6. View Related Products by Target Sirtuin

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C18H18N4OS2
Molecular Weight 370.492
Exact Mass 370.092194
LogP 4.60
Index of Refraction 1.661

 Synonyms

N-(5-benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide
Acetamide, 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-[5-(phenylmethyl)-2-thiazolyl]-
N-(5-Benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetamide