Transglutaminase
Transglutaminase structure
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Common Name | Transglutaminase | ||
|---|---|---|---|---|
| CAS Number | 80146-85-6 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H44O3H2O | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of TransglutaminaseTransglutaminase is an enzyme that forms crosslinks between protein molecules. Transglutaminase catalyses the formation of an isopeptide bond between the group of γ-carboxamides of glutamine residues and the first-order ε-amine groups of different compounds. Transglutaminase is involved in many physiological processes, including coagulation, antibacterial immune reactions and photosynthesis[1]. |
| Name | EC 2.3.2.13 |
|---|---|
| Synonym | More Synonyms |
| Description | Transglutaminase is an enzyme that forms crosslinks between protein molecules. Transglutaminase catalyses the formation of an isopeptide bond between the group of γ-carboxamides of glutamine residues and the first-order ε-amine groups of different compounds. Transglutaminase is involved in many physiological processes, including coagulation, antibacterial immune reactions and photosynthesis[1]. |
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| Related Catalog | |
| In Vitro | Transglutaminase activity can be increased by Co2+, Ba2+ and K+[1]. Microbial transglutaminases are inhibited by Zn2+, Cu2+, Hg2+ and Pb2+ ions which bind to the thiol group of cysteine in the active centre[1]. |
| Molecular Formula | C27H44O3H2O |
|---|---|
| Appearance of Characters | lyophilized powder |
| Storage condition | −20°C |
| Water Solubility | H2O: soluble1.0mg/mL, clear |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 22-24/25-26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | MA2370000 |
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Glycation and transglutaminase mediated glycosylation of fish gelatin peptides with glucosamine enhance bioactivity.
Food Chem. 142 , 285-93, (2014) A mixture of novel glycopeptides from glycosylation between cold water fish skin gelatin hydrolysates and glucosamine (GlcN) via transglutaminase (TGase), as well as glycation between fish gelatin hyd... |
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Inhibition of transglutaminase 2, a novel target for pulmonary fibrosis, by two small electrophilic molecules.
Am. J. Respir. Cell. Mol. Biol. 50(4) , 737-47, (2014) Idiopathic pulmonary fibrosis (IPF) is characterized by progressive fibrotic destruction of normal lung architecture. Due to a lack of effective treatment options, new treatment approaches are needed.... |
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Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells.
Biochim. Biophys. Acta 1853(1) , 201-12, (2015) Tissue transglutaminase (TG2) is a multifunctional protein cross-linking enzyme that has been implicated in apoptotic cell clearance but is also important in many other cell functions including cell a... |
| MFCD00132446 |
- Shanghai Nianxing Industrial Co., Ltd
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- Product Name: Transglutaminase
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