4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester

Modify Date: 2024-01-09 11:28:59

4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester Structure
4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester structure
Common Name 4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester
CAS Number 80625-18-9 Molecular Weight 234.274
Density 1.3±0.1 g/cm3 Boiling Point 442.5±33.0 °C at 760 mmHg
Molecular Formula C11H10N2O2S Melting Point 223ºC
MSDS USA Flash Point 221.4±25.4 °C

 Names

Name Methyl 2-amino-5-phenyl-1,3-thiazole-4-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 442.5±33.0 °C at 760 mmHg
Melting Point 223ºC
Molecular Formula C11H10N2O2S
Molecular Weight 234.274
Flash Point 221.4±25.4 °C
Exact Mass 234.046295
PSA 94.18000
LogP 1.82
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.632

 Synthetic Route

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4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester Structure

4-Thiazolecarbo...

CAS#:80625-18-9

Literature: FUJISAWA PHARMACEUTICAL CO., LTD., Patent: WO2004/67521 A1, 2004 ; Location in patent: Page 108-109 ;

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4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester Structure

4-Thiazolecarbo...

CAS#:80625-18-9

Literature: Mamedov, B. A.; Nuretdinov, I. A. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1987 , vol. 36, # 12 p. 2652 - 2653 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1987 , # 12 p. 2856 - 2857

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Detail
Literature: Cui, Yong-Mei; Huang, Qing-Qing; Xu, Jie; Chen, Ling-Ling; Li, Jing-Ya; Ye, Qi-Zhuang; Li, Jia; Nan, Fa-Jun Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3732 - 3736

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4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester Structure

4-Thiazolecarbo...

CAS#:80625-18-9

Literature: Mamedov, B. A.; Nuretdinov, I. A. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1987 , vol. 36, # 12 p. 2652 - 2653 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1987 , # 12 p. 2856 - 2857

~72%

4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester Structure

4-Thiazolecarbo...

CAS#:80625-18-9

Literature: Ladouceur, Gaetan H.; Schoen, William R.; Burke, Michael J. Patent: US2003/195352 A1, 2003 ; Location in patent: Page/Page column 30; 34 ;

 Synonyms

methyl 2-amino-5-methyl-thiazol-4-carboxylate
4-Thiazolecarboxylic acid, 2-amino-5-phenyl-, methyl ester
2-amino-4-carbomethoxy-5-phenylthiazole
Methyl 2-amino-5-phenyl-1,3-thiazole-4-carboxylate
2-amino-5-methyl-thiazole-4-carboxylic acid methyl ester
methyl 2-amino-5-phenyl-4-thiazolecarboxylate
2-amino-5-phenyl-thiazole-4-carboxylic acid methyl ester
Methyl 2-amino-5-methylthiazole-4-carboxylate
4-Thiazolecarboxylicacid,2-amino-5-phenyl-,methylester