3-phosphoglyceric acid
Modify Date: 2024-01-16 17:35:45
3-phosphoglyceric acid structure
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Common Name | 3-phosphoglyceric acid | ||
|---|---|---|---|---|
| CAS Number | 820-11-1 | Molecular Weight | 183.03300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C3H7O7P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3-phosphoglyceric acid3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation. |
| Name | 3-phosphoglyceric acid |
|---|---|
| Synonym | More Synonyms |
| Description | 3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation. |
|---|---|
| In Vitro | 3-Phosphoglyceric acid (400 µM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed[1]. 3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages[1]. In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation[1]. RT-PCR[1] Cell Line: Bone marrow-derived macrophages (BMDMs) Concentration: 400 µM Incubation Time: 24 hours Result: Enhanced Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification was also reversed. |
| References |
| Molecular Formula | C3H7O7P |
|---|---|
| Molecular Weight | 183.03300 |
| Exact Mass | 182.96900 |
| PSA | 142.59000 |
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CAS#:3443-57-0| D-3-phosphoglycerate |
| 4gwk |
| 3-phospho-D-glyceric acid |
| (2R)-2-hydroxy-3-phosphonatooxypropanoate |
| 3-phospho-D-glycerate |
| D-glycerate-3-P |
| D-Glycerate 3-phosphate |
| 3fjg |
| 3-P-D-glycerate |
| 3-phosphonato-D-glycerate |