2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine
Modify Date: 2024-01-30 20:27:05
2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine structure
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Common Name | 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine | ||
|---|---|---|---|---|
| CAS Number | 827030-33-1 | Molecular Weight | 299.75500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H14ClN3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amineMPI-0441138 is a potent inducer of apoptosis and growth inhibition (EC50 = 2 nM for both processes, based on caspase-3 activation and total cellular ATP, respectively) in T47D and HCT116 cells. |
| Name | 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine |
|---|
| Molecular Formula | C16H14ClN3O |
|---|---|
| Molecular Weight | 299.75500 |
| Exact Mass | 299.08300 |
| PSA | 38.25000 |
| LogP | 4.05970 |
|
~85%
2-chloro-N-(4-m... CAS#:827030-33-1 |
| Literature: Sirisoma, Nilantha; Kasibhatla, Shailaja; Pervin, Azra; Zhang, Hong; Jiang, Songchun; Willardsen, J. Adam; Anderson, Mark B.; Baichwal, Vijay; Mather, Gary G.; Jessing, Kevin; Hussain, Raouf; Hoang, Khanh; Pleiman, Christopher M.; Tseng, Ben; Drewe, John; Sui, Xiong Cai Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4771 - 4779 |
| Precursor 2 | |
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| DownStream 0 | |