2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate

Modify Date: 2024-01-10 17:34:33

2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate Structure
2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate structure
Common Name 2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate
CAS Number 845305-83-1 Molecular Weight 284.394
Density 1.1±0.1 g/cm3 Boiling Point 380.0±42.0 °C at 760 mmHg
Molecular Formula C15H28N2O3 Melting Point N/A
MSDS N/A Flash Point 183.6±27.9 °C

 Names

Name tert-butyl 4-piperidin-4-yloxypiperidine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 380.0±42.0 °C at 760 mmHg
Molecular Formula C15H28N2O3
Molecular Weight 284.394
Flash Point 183.6±27.9 °C
Exact Mass 284.209991
PSA 50.80000
LogP 1.45
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.507

 Safety Information

HS Code 2933399090

 Synthetic Route

~59%

2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate Structure

2-Methyl-2-prop...

CAS#:845305-83-1

Literature: SCHERING CORPORATION Patent: WO2009/45313 A2, 2009 ; Location in patent: Page/Page column 43-44 ; WO 2009/045313 A2

~%

2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate Structure

2-Methyl-2-prop...

CAS#:845305-83-1

Literature: GLAXO GROUP LIMITED Patent: WO2005/14571 A1, 2005 ; Location in patent: Page/Page column 18-19 ; WO 2005/014571 A1

~72%

2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate Structure

2-Methyl-2-prop...

CAS#:845305-83-1

Literature: Bailey, James M.; Bruton, Gordon; Huxley, Anthony; Johnstone, Vicky; Milner, Peter H.; Orlek, Barry S.; Stemp, Geoffrey Synlett, 2009 , # 7 p. 1051 - 1054

~%

2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate Structure

2-Methyl-2-prop...

CAS#:845305-83-1

Literature: Chao, Jianhua; Israiel, Mariam; Zheng, Junying; Aki, Cynthia Tetrahedron Letters, 2007 , vol. 48, # 5 p. 791 - 794

~%

2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate Structure

2-Methyl-2-prop...

CAS#:845305-83-1

Literature: Chao, Jianhua; Israiel, Mariam; Zheng, Junying; Aki, Cynthia Tetrahedron Letters, 2007 , vol. 48, # 5 p. 791 - 794

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-Piperidinecarboxylic acid, 4-(4-piperidinyloxy)-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate