Acetytastragaloside

Modify Date: 2024-01-07 23:32:25

Acetytastragaloside structure	Common Name	Acetytastragaloside
	CAS Number	84687-47-8	Molecular Weight	911.080
	Density	1.4±0.1 g/cm3	Boiling Point	902.9±65.0 °C at 760 mmHg
	Molecular Formula	C₄₇H₇₄O₁₇	Melting Point	N/A
	MSDS	N/A	Flash Point	254.5±27.8 °C

Use of Acetytastragaloside

Acetylastragaloside I is a glycoside that can be isolated from the roots of Astragalus baibutensis. Acetylastragaloside I is the first cycloartane-type triterpene with remarkable trypanocidal activity with IC50 values of 9.5 and 5.0 μg/mL for T. brucei rhodesiense and T. cruzi, respectively. Acetylastragaloside I can be used for the research of trypanosome infection[1].

Name	acetylastragaloside I
Synonym	More Synonyms

Description	Acetylastragaloside I is a glycoside that can be isolated from the roots of Astragalus baibutensis. Acetylastragaloside I is the first cycloartane-type triterpene with remarkable trypanocidal activity with IC50 values of 9.5 and 5.0 μg/mL for T. brucei rhodesiense and T. cruzi, respectively. Acetylastragaloside I can be used for the research of trypanosome infection[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 9.5 μg/mL (T. brucei rhodesiense), 5.0 μg/mL (T. cruzi), ＞30 μg/mL (L. donovani), ＞20 μg/mL (P. falciparum), 24.2 μg/mL (L6 cells)[1]
In Vitro	Acetylastragaloside I (0.123-90 μg/mL; 72-96 h) shows in vitro antiprotozoal activity to T. brucei rhodesiense, T. cruzi, L. donovani and P. falciparum with IC50 values of 9.5, 5.0, ＞30 and ＞20 μg/mL, respectively[1]. Acetylastragaloside I (0.123-90 μg/mL; 72 h) exhibits cytotoxicity effects to rat skeletal myoblasts (L6) cells[1]. Cell Cytotoxicity Assay[1] Cell Line: Rat skeletal myoblasts (L6) cell line Concentration: 0.123-90 μg/mL Incubation Time: 72 hours Result: Showed cytotoxicity to L6 cells with an IC50 value of 24.2 μg/mL.

Density	1.4±0.1 g/cm3
Boiling Point	902.9±65.0 °C at 760 mmHg
Molecular Formula	C₄₇H₇₄O₁₇
Molecular Weight	911.080
Flash Point	254.5±27.8 °C
Exact Mass	910.492615
PSA	246.43000
LogP	3.10
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.586