2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine

Modify Date: 2024-01-29 16:21:55

2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine Structure
2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine structure
Common Name 2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine
CAS Number 84761-70-6 Molecular Weight 395.39700
Density 1.202g/cm3 Boiling Point 469.9ºC at 760 mmHg
Molecular Formula C20H23F2NO5 Melting Point N/A
MSDS N/A Flash Point 238ºC

 Names

Name diethyl 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

 Chemical & Physical Properties

Density 1.202g/cm3
Boiling Point 469.9ºC at 760 mmHg
Molecular Formula C20H23F2NO5
Molecular Weight 395.39700
Flash Point 238ºC
Exact Mass 395.15400
PSA 73.86000
LogP 3.97780
Index of Refraction 1.505

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7969300
CHEMICAL NAME :
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2-(difluoromethoxy)phenyl)-2,6-dimethy l-, diethyl ester
CAS REGISTRY NUMBER :
84761-70-6
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H23-F2-N-O5
MOLECULAR WEIGHT :
395.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
110 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Vascular - regional or general arteriolar or venous dilation
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,817,1982
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