Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate

Modify Date: 2024-01-10 16:44:24

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate structure	Common Name	Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate
	CAS Number	862283-69-0	Molecular Weight	329.82100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₀ClNO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	Methyl (3R,4S)-1-benzyl-4-(4-chlorophenyl)-3-pyrrolidinecarboxyla te
Synonym	More Synonyms

Molecular Formula	C₁₉H₂₀ClNO₂
Molecular Weight	329.82100
Exact Mass	329.11800
PSA	29.54000
LogP	3.66650

(3R,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidine-3-carboxylic acid methyl ester structure

(3R,4R)-1-benzy...

CAS#:1310819-13-6

~85%

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate Structure

Trans-Methyl 1-...

CAS#:862283-69-0

Literature: F. HOFFMANN-LA ROCHE AG; KNUST, Henner; KOBLET, Andreas; NETTEKOVEN, Matthias; RATNI, Hasane; RIEMER, Claus; VIFIAN, Walter Patent: WO2011/85886 A1, 2011 ; Location in patent: Page/Page column 93 ; WO 2011/085886 A1

(S)-4-benzyl-3-((3S,4R)-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carbonyl)oxazolidin-2-one structure

(S)-4-benzyl-3-...

CAS#:862283-67-8

Dimethyl Carbonate structure

Dimethyl Carbonate

CAS#:616-38-6

~81%

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate Structure

Trans-Methyl 1-...

CAS#:862283-69-0

Literature: Pfizer Inc Patent: US2005/176772 A1, 2005 ; Location in patent: Page/Page column 62-63 ; US 20050176772 A1

Ethyl 3-(4-chlorophenyl)-2-propynoate structure

Ethyl 3-(4-chlo...

CAS#:20026-96-4

~%

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate Structure

Trans-Methyl 1-...

CAS#:862283-69-0

Literature: Knust, Henner; Koblet, Andreas; Nettekoven, Matthias; Ratni, Hasane; Riemer, Claus; Vifian, Walter Patent: US2011/144081 A1, 2011 ; US 20110144081 A1

1-Benzyl-4-(4-chloro-phenyl)-2,5-dihydro-1H-pyrrole-3-carboxylic acid structure

1-Benzyl-4-(4-c...

CAS#:1229236-32-1

~%

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate Structure

Trans-Methyl 1-...

CAS#:862283-69-0

Literature: Knust, Henner; Koblet, Andreas; Nettekoven, Matthias; Ratni, Hasane; Riemer, Claus; Vifian, Walter Patent: US2011/144081 A1, 2011 ; US 20110144081 A1

1-Chloro-4-iodobenzene structure

1-Chloro-4-iodo...

CAS#:637-87-6

~%

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate Structure

Trans-Methyl 1-...

CAS#:862283-69-0

Literature: Knust, Henner; Koblet, Andreas; Nettekoven, Matthias; Ratni, Hasane; Riemer, Claus; Vifian, Walter Patent: US2011/144081 A1, 2011 ; US 20110144081 A1

N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine structure

N-(Methoxymethy...

CAS#:93102-05-7

~%

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate Structure

Trans-Methyl 1-...

CAS#:862283-69-0

Literature: Knust, Henner; Koblet, Andreas; Nettekoven, Matthias; Ratni, Hasane; Riemer, Claus; Vifian, Walter Patent: US2011/144081 A1, 2011 ; US 20110144081 A1

(3R,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidine-3-carboxylic acid structure

(3R,4R)-1-benzy...

CAS#:1310819-12-5

~%

Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate Structure

Trans-Methyl 1-...

CAS#:862283-69-0

Literature: Knust, Henner; Koblet, Andreas; Nettekoven, Matthias; Ratni, Hasane; Riemer, Claus; Vifian, Walter Patent: US2011/144081 A1, 2011 ; US 20110144081 A1

Precursor 7
CAS#:1310819-13-6 (3R,4R)-1-benzy... CAS#:862283-67-8 (S)-4-benzyl-3-... CAS#:616-38-6 Dimethyl Carbonate CAS#:20026-96-4 Ethyl 3-(4-chlo...
CAS#:637-87-6 1-Chloro-4-iodo... CAS#:93102-05-7 N-(Methoxymethy... CAS#:1310819-12-5 (3R,4R)-1-benzy...
DownStream 1
CAS#:862283-71-4 4-FORMYLBENZENE...

Trans-methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate