tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate

Modify Date: 2024-01-18 20:00:59

tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate Structure
tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate structure
Common Name tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate
CAS Number 864068-79-1 Molecular Weight 298.40100
Density 1.215g/cm3 Boiling Point 439.5ºC at 760 mmHg
Molecular Formula C14H22N2O3S Melting Point N/A
MSDS N/A Flash Point 219.6ºC

 Names

Name tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.215g/cm3
Boiling Point 439.5ºC at 760 mmHg
Molecular Formula C14H22N2O3S
Molecular Weight 298.40100
Flash Point 219.6ºC
Exact Mass 298.13500
PSA 90.90000
LogP 2.68780
Index of Refraction 1.555

 Synthetic Route

~81%

tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate Structure

tert-butyl 4-[4...

CAS#:864068-79-1

Literature: BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C. Patent: WO2013/163279 A1, 2013 ; Location in patent: Paragraph 00312 ;

~%

tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate Structure

tert-butyl 4-[4...

CAS#:864068-79-1

Literature: BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C. Patent: WO2013/163279 A1, 2013 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

1-(1,1-dimethylethyl) 4-[4-(hydroxymethyl)-2-thiazolyl]-1-piperidinecarboxylate
tert-butyl 4-(4-(hydroxymethyl)thiazol-2-yl)piperidine-1-carboxylate