Gsk270822a
Modify Date: 2024-01-03 18:21:32
Gsk270822a structure
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Common Name | Gsk270822a | ||
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| CAS Number | 864082-23-5 | Molecular Weight | 396.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H20N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Gsk270822aGSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively. |
| Name | GSK270822A |
|---|
| Description | GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively. |
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| In Vitro | GSK270822A inhibits rat aortic ring dilation with IC50 of 76nM[1]. |
| References | 1. Identification and Structure-Function Analysis of Subfamily Selective G Protein-Coupled Receptor Kinase Inhibitors. By Homan, Kristoff T.; Larimore, Kelly M.; Elkins, Jonathan M.; Szklarz, Marta; Knapp, Stefan; Tesmer, John J. G. From ACS Chemical Biology (2015), 10(1), 310-319. |
| Molecular Formula | C24H20N4O2 |
|---|---|
| Molecular Weight | 396.44 |