KKL-40
Modify Date: 2024-01-03 14:47:31
KKL-40 structure
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Common Name | KKL-40 | ||
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| CAS Number | 865285-47-8 | Molecular Weight | 351.255 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H9F4N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KKL-40A small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture; exhibited exceptional antimicrobial activity against both attenuated (LVS) and fully virulent strains of F. tularensis (Schu S4) in vitro with MIC of 0.12 and 0.44 ug/mL, respectively; arrests intracellular growth of F. tularensis during all stages of infection, does not affect macrophage viability or function. |
| Name | N-[5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl]-3-(trifluoromethyl)benzamide |
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| Synonym | More Synonyms |
| Description | A small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture; exhibited exceptional antimicrobial activity against both attenuated (LVS) and fully virulent strains of F. tularensis (Schu S4) in vitro with MIC of 0.12 and 0.44 ug/mL, respectively; arrests intracellular growth of F. tularensis during all stages of infection, does not affect macrophage viability or function. |
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| References | References 1. Goralski TD, et al. Antimicrob Agents Chemother. 2016 May 23;60(6):3276-82. View Related Products by Target Bacterial |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C16H9F4N3O2 |
| Molecular Weight | 351.255 |
| Exact Mass | 351.063080 |
| LogP | 4.43 |
| Index of Refraction | 1.570 |
| N-[5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl]-3-(trifluoromethyl)benzamide |
| Benzamide, N-[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]-3-(trifluoromethyl)- |