2,6-xylidine

Modify Date: 2024-01-02 10:51:24

2,6-xylidine Structure
2,6-xylidine structure
 Common Name 2,6-xylidine
CAS Number 87-62-7 Molecular Weight 121.180
Density 1.0±0.1 g/cm3 Boiling Point 217.9±0.0 °C at 760 mmHg
Molecular Formula C8H11N Melting Point 10-12 °C(lit.)
MSDS Chinese USA Flash Point 91.1±0.0 °C
Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09		 Signal Word Warning

 Names

Name 2,6-dimethylaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 217.9±0.0 °C at 760 mmHg
Melting Point 10-12 °C(lit.)
Molecular Formula C8H11N
Molecular Weight 121.180
Flash Point 91.1±0.0 °C
Exact Mass 121.089149
PSA 26.02000
LogP 1.86
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.559
Water Solubility 7.5 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE9275000
CHEMICAL NAME :
2,6-Xylidine
CAS REGISTRY NUMBER :
87-62-7
BEILSTEIN REFERENCE NO. :
0636332
LAST UPDATED :
199710
DATA ITEMS CITED :
19
MOLECULAR FORMULA :
C8-H11-N
MOLECULAR WEIGHT :
121.20
WISWESSER LINE NOTATION :
ZR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
840 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Blood - changes in spleen
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
707 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3150 mg/kg/20D-C
TOXIC EFFECTS :
Blood - changes in spleen
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6200 mg/kg/2W-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13300 mg/kg/4W-I
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20150 mg/kg/13W-I
TOXIC EFFECTS :
Brain and Coverings - changes in brain weight Liver - changes in liver weight Blood - changes in other cell count (unspecified)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
107 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Endocrine - tumors

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
301 mg/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,323,1993 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,323,1993 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,323,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7951 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4354 (estimated) No. of Female Employees: 729 (estimated)

 Safety Information

Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning
Hazard Statements H302 + H312 + H332-H315-H335-H351-H411
Precautionary Statements P261-P273-P280
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;N:Dangerousfortheenvironment;
Risk Phrases R20/21/22;R37/38;R40;R51/53
Safety Phrases S23-S25-S36/37-S61
RIDADR UN 1711 6.1/PG 2
WGK Germany 2
RTECS ZE9275000
Packaging Group II
Hazard Class 6.1
HS Code 29214910

 Synthetic Route

 Customs

HS Code 2921430090
Summary HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles30

More Articles
Simultaneous Determination of Xylazine and 2,6-Xylidine in Blood and Urine by Auto Solid-Phase Extraction and Ultra High Performance Liquid Chromatography Coupled with Quadrupole-Time of Flight Mass Spectrometry.

J. Anal. Toxicol. 39 , 444-50, (2015)

Xylazine as veterinary medicine for sedation, but intoxication cases in humans were identified in the last few years. A highly sensitive method is required for analyzing xylazine and its metabolites i...

A Novel Method for Assessing Drug Degradation Product Safety Using Physiologically-Based Pharmacokinetic Models and Stochastic Risk Assessment.

J. Pharm. Sci. 104 , 3101-19, (2015)

Patient safety risk due to toxic degradation products is a potentially critical quality issue for a small group of useful drug substances. Although the pharmacokinetics of toxic drug degradation produ...

Concentrations of dimethylaniline and other metabolites in milk and tissues of dairy cows treated with lidocaine.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 1256-64, (2015)

Lidocaine is a topical anaesthetic drug used in dairy cows for laparotomy (caesarean section, abomasal displacement). Because there are no registered drugs for this indication, it can be applied under...

 Synonyms

o-Xylidine
2-Amino-1,3-xylene
2,6-dimethyl-aniline
Benzene, 2-amino-1,3-dimethyl-
1-amino-2,6-dimethybenzene
Benzenamine,2,6-dimethyl
2,6-xylidine
2,6-dimethylphenylamine
2,6-dimethylbenzeneamine
aniline, 2,6-dimethyl-
MFCD00007747
2-amino-1,3-dimethylbenzene
Benzenamine, 2,6-dimethyl-
2,6-Dimethylbenzenamine
2,6-Dimethylaniline
2-Amino-m-xylene
2,5-DIMETHOXYTOLUENE
1-amino-2,6-dimethylbenzene
2,6-methylaniline
EINECS 201-758-7
2,6-dimethyl aniline
Bupivacaine Impurity 8
Top Suppliers:I want be here

Get all suppliers and price by the below link:

2,6-xylidine suppliers

2,6-xylidine price

Related Compounds: More...
2,6-xylidine
1092805-08-7
2,6-xylidine
21436-98-6
3-nitro-2,6-xylidine
67083-28-7
4-bromo-2,6-xylidine
24596-19-8
4-Ethoxy-2,6-xylidine
54220-95-0
3-Hydroxy-2,6-xylidine
100445-96-3
N-(2-methoxyethyl)-2,6-xylidine
50563-55-8
N-methyl-N-nitroso-2,6-xylidine
24699-12-5
N-(2-Nitrobenzylidene)-2,6-xylidine
109772-86-3
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
7-Fluoro-8-methylquinolin-5-amine
1863580-81-7
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
tert-Butyl-DL-alanine
1375289-11-4
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
849349-65-1
Chemsrc provides 2,6-xylidine(CAS#:87-62-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 2,6-xylidine are included as well.>> amp version: 2,6-xylidine

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved