m-PEG16-SH

Modify Date: 2024-01-05 10:37:33

m-PEG16-SH Structure
m-PEG16-SH structure
Common Name m-PEG16-SH
CAS Number 874820-38-9 Molecular Weight 752.95
Density N/A Boiling Point N/A
Molecular Formula C33H68O16S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG16-SH


m-PEG16-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG16-SH

 m-PEG16-SH Biological Activity

Description m-PEG16-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C33H68O16S
Molecular Weight 752.95