(4R,5S)-5-(3,5-bis(trifluoroMethyl)phenyl)-4-Methyloxazolidin-2-one
Modify Date: 2024-01-03 19:15:19
(4R,5S)-5-(3,5-bis(trifluoroMethyl)phenyl)-4-Methyloxazolidin-2-one structure
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Common Name | (4R,5S)-5-(3,5-bis(trifluoroMethyl)phenyl)-4-Methyloxazolidin-2-one | ||
|---|---|---|---|---|
| CAS Number | 875444-08-9 | Molecular Weight | 313.196 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 329.5±42.0 °C at 760 mmHg | |
| Molecular Formula | C12H9F6NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 153.1±27.9 °C | |
| Name | (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one |
|---|---|
| Synonym | More Synonyms |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 329.5±42.0 °C at 760 mmHg |
| Molecular Formula | C12H9F6NO2 |
| Molecular Weight | 313.196 |
| Flash Point | 153.1±27.9 °C |
| Exact Mass | 313.053741 |
| PSA | 38.33000 |
| LogP | 3.31 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.433 |
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~98%
(4R,5S)-5-(3,5-... CAS#:875444-08-9 |
| Literature: MERCK and CO., INC. Patent: WO2007/81569 A2, 2007 ; Location in patent: Page/Page column 34-35 ; |
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~%
(4R,5S)-5-(3,5-... CAS#:875444-08-9 |
| Literature: MERCK and CO., INC. Patent: WO2006/14357 A1, 2006 ; Location in patent: Page/Page column 51-52 ; |
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~%
(4R,5S)-5-(3,5-... CAS#:875444-08-9 |
| Literature: AMIRA PHARMACEUTICALS, INC. Patent: WO2009/108720 A2, 2009 ; Location in patent: Page/Page column 132 ; WO 2009/108720 A2 |
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Detail
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| Literature: MERCK and CO., INC. Patent: WO2007/81571 A2, 2007 ; Location in patent: Page/Page column 41 ; |
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~%
(4R,5S)-5-(3,5-... CAS#:875444-08-9 |
| Literature: Ogawa, Takanori; Kumagai, Naoya; Shibasaki, Masakatsu Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6196 - 6201 Angew. Chem., 2013 , vol. 125, # 24 p. 6316 - 6321 |
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![[(S)-2-(3,5-bis-trifluoromethyl-phenyl)-2-hydroxy-1-methyl-ethyl]-carbamic acid benzyl ester structure](https://image.chemsrc.com/caspic/003/1182350-90-8.png)
![(1R,2S)-2-amino-1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol structure](https://image.chemsrc.com/caspic/062/1152029-16-7.png)
![(1R,2R)-2-amino-1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol structure](https://image.chemsrc.com/caspic/426/1402799-11-4.png)
CAS#:875446-37-0| (4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-1,3-oxazolidin-2-one |
| 2-Oxazolidinone, 5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-, (4S,5R)- |
| 2-Oxazolidinone,5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-,(4S,5R) |
| (4S,5R)-5-(3,5-bis-trifluoromethyl-phenyl)-4-methyl-oxazolidin-2-one |
| (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one |
| (4R,5S)-5-(3,5-bis(trifluoroMethyl)phenyl)-4-Methyloxazolidin-2-one |
| Anacetrapib Intermediate 2 |