2-Nitroaniline

Modify Date: 2024-01-02 12:22:09

2-Nitroaniline Structure
2-Nitroaniline structure
Common Name 2-Nitroaniline
CAS Number 88-74-4 Molecular Weight 138.124
Density 1.3±0.1 g/cm3 Boiling Point 284.9±13.0 °C at 760 mmHg
Molecular Formula C6H6N2O2 Melting Point 70-73 °C(lit.)
MSDS Chinese USA Flash Point 126.1±19.8 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

 Names

Name 2-nitroaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 284.9±13.0 °C at 760 mmHg
Melting Point 70-73 °C(lit.)
Molecular Formula C6H6N2O2
Molecular Weight 138.124
Flash Point 126.1±19.8 °C
Exact Mass 138.042923
PSA 71.84000
LogP 1.83
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.634
Water Solubility 1.1 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BY6650000
CHEMICAL NAME :
Aniline, o-nitro-
CAS REGISTRY NUMBER :
88-74-4
LAST UPDATED :
199710
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C6-H6-N2-O2
MOLECULAR WEIGHT :
138.14
WISWESSER LINE NOTATION :
ZR BNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1070 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2350 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
9441 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
10 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,273,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84091 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 336 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84091 No. of Facilities: 54 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1612 (estimated) No. of Female Employees: 455 (estimated)

 Safety Information

Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger
Hazard Statements H301-H311-H331-H373-H412
Precautionary Statements P261-P273-P280-P301 + P310-P311
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic
Risk Phrases R23/24/25;R33;R52/53
Safety Phrases S28-S36/37-S45-S61-S28A-S16-S7
RIDADR UN 1661 6.1/PG 2
WGK Germany 2
RTECS BY6650000
Packaging Group II
Hazard Class 6.1
HS Code 2921420090

 Synthetic Route

 Customs

HS Code 2921420090
Summary HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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 Synonyms

1-amino-2-nitro-benzene
Nitroaniline
Devol Orange B
EINECS 201-855-4
Benzenamine, 2-nitro-
Azoic Diazo Component 6
aniline, 2-nitro-
MFCD00007687
aniline, nitro-
o-Nitraniline
1-nitro-2-aminobenzene
2-nitrophenylamine
2-Aminonitrobenzene
1-Amino-2-nitrobenzene
Benzenamine,2-nitro
ortho-nitro-aniline
2-Nitrobenzenamine
o-nitroaniline
2-nitro-aniline
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