R-360163

Modify Date: 2024-01-14 20:51:49

R-360163 Structure
R-360163 structure
Common Name R-360163
CAS Number 883791-50-2 Molecular Weight 392.365
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C20H16N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of R-360163


R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay; displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

 Names

Name MFCD00614570
Synonym More Synonyms

 R-360163 Biological Activity

Description R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay; displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
References References 1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11. View Related Products by Target Beta-catenin

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C20H16N4O5
Molecular Weight 392.365
Exact Mass 392.112061
LogP 2.62
Index of Refraction 1.669

 Synonyms

Benzoic acid, 3-[[2-[(2Z)-2-[1,2-dihydro-2-oxo-1-(2-propen-1-yl)-3H-indol-3-ylidene]hydrazinyl]-1,2-dioxoethyl]amino]-
3-({[(2Z)-2-(1-Allyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino](oxo)acetyl}amino)benzoic acid
MFCD00614570