fluxofenim
Modify Date: 2024-01-10 12:22:39
fluxofenim structure
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Common Name | fluxofenim | ||
|---|---|---|---|---|
| CAS Number | 88485-37-4 | Molecular Weight | 309.66900 | |
| Density | 1.43g/cm3 | Boiling Point | 309.5ºC at 760 mmHg | |
| Molecular Formula | C12H11ClF3NO3 | Melting Point | 25°C | |
| MSDS | Chinese USA | Flash Point | 141ºC | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
| Name | fluxofenim |
|---|---|
| Synonym | More Synonyms |
| Density | 1.43g/cm3 |
|---|---|
| Boiling Point | 309.5ºC at 760 mmHg |
| Melting Point | 25°C |
| Molecular Formula | C12H11ClF3NO3 |
| Molecular Weight | 309.66900 |
| Flash Point | 141ºC |
| Exact Mass | 309.03800 |
| PSA | 40.05000 |
| LogP | 2.99590 |
| Index of Refraction | 1.509 |
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Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE Product identifiers Product name: Fluxofenim CAS-No.: 88485-37-4 Relevant identified uses of the substance or mixture and uses advised against Identified uses: Laboratory chemicals, Manufacture of substances Section2. HAZARDS IDENTIFICATION Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Acute toxicity, Inhalation (Category 2) Acute toxicity, Dermal (Category 4) Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Acute aquatic toxicity (Category 1) Classification according to EU Directives 67/548/EEC or 1999/45/EC Harmful in contact with skin and if swallowed. Irritating to skin. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Label elements Labelling according Regulation (EC) No 1272/2008 [CLP] Pictogram Signal wordDanger Hazard statement(s) H302Harmful if swallowed. H312Harmful in contact with skin. H315Causes skin irritation. H330Fatal if inhaled. H400Very toxic to aquatic life. Precautionary statement(s) P260Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P273Avoid release to the environment. P280Wear protective gloves/ protective clothing. P284Wear respiratory protection. P310Immediately call a POISON CENTER or doctor/ physician. Supplemental Hazardnone Statements According to European Directive 67/548/EEC as amended. Hazard symbol(s) R-phrase(s) R21/22Harmful in contact with skin and if swallowed. R38Irritating to skin. R50/53Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. S-phrase(s) S36/37/39Wear suitable protective clothing, gloves and eye/face protection. S60This material and its container must be disposed of as hazardous waste. S61Avoid release to the environment. Refer to special instructions/ Safety data sheets. Caution - substance not yet tested completely. Other hazards - none Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substances Formula: C12H11ClF3NO3 Molecular Weight: 309,67 g/mol ComponentConcentration Fluxofenim CAS-No.88485-37-4- Section4. FIRST AID MEASURES Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed Indication of any immediate medical attention and special treatment needed no data available Section5. FIREFIGHTING MEASURES Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas, Hydrogen fluoride Carbon oxides, nitrogen oxides (NOx), Hydrogen fluoride Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available Section6. ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. Section7. HANDLING AND STORAGE Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Normal measures for preventive fire protection. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Specific end uses no data available Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Section9. PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties a) AppearanceForm: liquid b) Odourno data available c) Odour Thresholdno data available d) pHno data available e) Melting point/freezingno data available point f) Initial boiling point and no data available boiling range g) Flash pointno data available h) Evaporation rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerno data available flammability or explosive limits k) Vapour pressureno data available l) Vapour densityno data available m) Relative densityno data available n) Water solubilityno data available o) Partition coefficient: n- no data available octanol/water p) Autoignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesno data available t) Oxidizing propertiesno data available Other safety information no data available Section10. STABILITY AND REACTIVITY Reactivity no data available Chemical stability no data available Possibility of hazardous reactions no data available Conditions to avoid no data available Incompatible materials Strong oxidizing agents Hazardous decomposition products Other decomposition products - no data available Section11. TOXICOLOGICAL INFORMATION Information on toxicological effects Acute toxicity LD50 Oral - rat - 669 mg/kg LC50 Inhalation - rat - 4 h - > 1.210 mg/m3 LD50 Dermal - rabbit - 1.480 mg/kg Remarks: Diarrhoea Gastrointestinal:Other changes. Other changes Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity no data available Carcinogenicity IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects InhalationMay be fatal if inhaled. Causes respiratory tract irritation. Ingestion Harmful if swallowed. SkinHarmful if absorbed through skin. Causes skin irritation. Additional Information RTECS: KM5638200 Section12. ECOLOGICAL INFORMATION Toxicity Toxicity to fishLC50 - Oncorhynchus mykiss (rainbow trout) - 0,86 mg/l - 96,0 h Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment no data available Other adverse effects Very toxic to aquatic life. Section13. DISPOSAL CONSIDERATIONS Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging Dispose of as unused product. Section14. TRANSPORT INFORMATION UN number ADR/RID: 3082IMDG: 3082IATA: 3082 UN proper shipping name ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Fluxofenim) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Fluxofenim) IATA:Environmentally hazardous substance, liquid, n.o.s. (Fluxofenim) Transport hazard class(es) ADR/RID: 9IMDG: 9IATA: 9 Packaging group ADR/RID: IIIIMDG: IIIIATA: III Environmental hazards ADR/RID: yesIMDG Marine pollutant: yesIATA: yes Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids. SECTION 15 - REGULATORY INFORMATION N/A SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H312-H315-H330-H400 |
| Precautionary Statements | P260-P273-P280-P284-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn: Harmful;N: Dangerous for the environment; |
| Risk Phrases | R21/22 |
| Safety Phrases | 36/37/39-60-61 |
| RIDADR | UN3082 9/PG 3 |
| RTECS | KM5638200 |
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Festuca arundinacea, glutathione S-transferase and herbicide safeners: a preliminary case study to reduce herbicidal pollution.
J. Environ. Sci. Health B 44(8) , 805-9, (2009) The expression of glutathione S-transferase (GST) activity in Festuca arundinacea was investigated in response to the following herbicide safeners: benoxacor, cloquintocet-mexyl, fenchlorazol-ethyl, f... |
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Induction of glutathione S-transferases in Arabidopsis by herbicide safeners.
Plant Physiol. 130(3) , 1497-505, (2002) Herbicide safeners increase herbicide tolerance in cereals but not in dicotyledenous crops. The reason(s) for this difference in safening is unknown. However, safener-induced protection in cereals is ... |
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Organ-specific expression of glutathione S-transferases and the efficacy of herbicide safeners in Arabidopsis.
Plant Physiol. 140(1) , 167-75, (2006) The functions of plant glutathione S-transferases (GSTs) under normal growth conditions are poorly understood, but their activity as detoxification enzymes has been harnessed in agriculture for select... |
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| (4-chlorobenzoylmethylene)triphenylphosphorane |
| 1-(4-Chlorophenyl)-2-(3-pyridinyl)ethanone |
| 1-(4-chlorophenyl)-2-(triphenylphosphanylidene)ethanone |
| Ph3P=COC6H4Cl |
| 1-(4-chlorophenyl)-2-(triphenylphosphosphanylidene)ethanone |
| 1-(4-chlorophenyl)-2-(triphenylphosphoranylidene)ethanone |
| 1-(4-chlorophenyl)-2,2,2-trifluoro-1-ethanone O-(1,3-dioxolan-2-ylmethyl)oxime |
| 4’-chloro-2,2,2-trifluoroacetophenone (EZ)-O-1,3-dioxolan-2-ylmethyloxime |
| 1-(4-chloro-phenyl)-2-pyridin-3-yl-ethanone |
| (p-Chlorobenzoylmethylene)triphenylphosphorane |
| [(p-chlorobenzoyl)methylene]triphenylphosphoran |
| 1-(4-chlorophenyl)-1-(1,3-dioxolan-2-ylmethoximino)-2,2,2-trifluoroethane |
| (pyrid-3-ylmethyl)-(4-chlorophenyl)-ketone |
| (1Z)-1-(4-Chlorophenyl)-N-(1,3-dioxolan-2-ylmethoxy)-2,2,2-triflu oroethanimine |
| 1-(4-chlorophenyl)-2,2,2-trifluoroethanone O-(1,3-dioxolan-2-ylmethyl)oxime |
| 4'-chloro-2-(3-pyridyl)-acetophenone |
| 1-(4-CHLOROPHENYL)-2-(3-PYRIDYL)ETHANONE |