5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(4-morpholinyl)-a-lyxo-hexopyranosyl]oxy]-,hydrochloride, (8S,10S)- (9CI)

Modify Date: 2024-04-07 04:41:15

5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(4-morpholinyl)-a-lyxo-hexopyranosyl]oxy]-,hydrochloride, (8S,10S)- (9CI) Structure
5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(4-morpholinyl)-a-lyxo-hexopyranosyl]oxy]-,hydrochloride, (8S,10S)- (9CI) structure
Common Name 5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(4-morpholinyl)-a-lyxo-hexopyranosyl]oxy]-,hydrochloride, (8S,10S)- (9CI)
CAS Number 89196-04-3 Molecular Weight 650.07000
Density N/A Boiling Point 842.4ºC at 760 mmHg
Molecular Formula C31H36ClNO12 Melting Point N/A
MSDS N/A Flash Point 463.2ºC

 Names

Name 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(4-morpholinyl)-.α.-L-lyxo-hexopyranosyl]oxy]-, hydrochloride, (8S-cis)
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 842.4ºC at 760 mmHg
Molecular Formula C31H36ClNO12
Molecular Weight 650.07000
Flash Point 463.2ºC
Exact Mass 649.19300
PSA 192.52000
LogP 1.11470

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QI9426040
CHEMICAL NAME :
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-(hydroxyacetyl)-1-methoxy-10-(( 2,3,6-trideoxy- 3-(4-morpholinyl)-alpha-lyxo-hexopyranosyl)oxy)-6,8,1 1-trihydroxy-, hydrochloride, (8S-cis)-
CAS REGISTRY NUMBER :
89196-04-3
LAST UPDATED :
199303
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C31-H35-N-O12.Cl-H
MOLECULAR WEIGHT :
650.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
70 ug/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Musculoskeletal - other changes Nutritional and Gross Metabolic - dehydration
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-211144
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
90 ug/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Blood - changes in bone marrow (not otherwise specified) Musculoskeletal - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-211144

 Synonyms

Morpholinoadriamycin
(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-10-[(2S,4S,5S,6S)-5-hydroxy-6-methyl-4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride