FICIN

Modify Date: 2024-01-05 18:46:45

FICIN Structure
FICIN structure
Common Name FICIN
CAS Number 9001-33-6 Molecular Weight 226.232
Density 1.4±0.1 g/cm3 Boiling Point 656.2±55.0 °C at 760 mmHg
Molecular Formula C9H14N4O3 Melting Point N/A
MSDS Chinese USA Flash Point 350.7±31.5 °C
Symbol GHS08
GHS08
Signal Word Danger

 Use of FICIN


Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig (Ficus carica). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments[1][2].

 Names

Name Ficin
Synonym More Synonyms

 FICIN Biological Activity

Description Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig (Ficus carica). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments[1][2].
Related Catalog
In Vitro Ficain (0-8 µg/mL) 以酪蛋白为底物,在 280 nm 处测量三氯乙酸滤液的吸光度,检测 Ficin 活性[2]。 Ficain (0-200 µg/mL) 在 p-nitrophenyl carbobenzoxyglycinate 为底物时,以剂量依赖性方式增加 400 nm 处的吸光度[2]。
References

[1]. Morellon-Sterling R, et al. Ficin: A protease extract with relevance in biotechnology and biocatalysis. Int J Biol Macromol. 2020 Nov 1;162:394-404.  

[2]. Liener I E, Friedenson B. [17] Ficin[M]//Methods in enzymology. Academic Press, 1970, 19: 261-273.

[3]. RatanaKhanokchai K. Purification and Characterization of Cysteine Proteinase from Some Vegetables and fruits[J]. 2009.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 656.2±55.0 °C at 760 mmHg
Molecular Formula C9H14N4O3
Molecular Weight 226.232
Flash Point 350.7±31.5 °C
Exact Mass 226.106583
LogP -2.17
Appearance of Characters saline suspension | tan
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.591
Storage condition 2-8°C
Water Solubility Soluble in cold water.

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H334
Precautionary Statements P261-P342 + P311
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn,Xi
Risk Phrases 36/37/38-42
Safety Phrases 26-36-36/37-24-22-45-23
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LK3675000

 Articles26

More Articles
Various forms of rabbit plasma alpha-1-antiproteinase.

Biochem. Mol. Biol. Int. 46(1) , 27-34, (1998)

Amino acid sequencing of the ficin-derived C-terminal fragments of alpha-1-antiproteinase (also called alpha-1-antitrypsin or alpha-1-proteinase inhibitor) prepared from rabbit plasma revealed the pre...

Characterization of acid-induced molten globule like state of ficin.

Int. J. Biol. Macromol. 45(3) , 248-54, (2009)

Effect of pH on the conformational behaviour of ficin (EC 3.4.22.3), a cysteine protease from the latex of Ficus carica was monitored by circular dichroism, fluorescence spectroscopy, ANS binding and ...

Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations.

Biochem. J. 357(Pt 2) , 343-52, (2001)

The possibility of a slow post-acylation conformational change during catalysis by cysteine proteinases was investigated by using a new chromogenic substrate, N-acetyl-Phe-Gly methyl thionoester, four...

 Synonyms

2-[(3-Aminopropanoyl)amino]-3-(1H-imidazol-4-yl)propanoic acid
Histidine, β-alanyl-
MFCD00081597
b-Alanylhistidine
β-Alanylhistidine
carnosine
N-(3-Aminopropanoyl)histidine