Glucose-6-phosphate dehydrogenase

Modify Date: 2024-01-01 18:20:29

Glucose-6-phosphate dehydrogenase Structure
Glucose-6-phosphate dehydrogenase structure
Common Name Glucose-6-phosphate dehydrogenase
CAS Number 9001-40-5 Molecular Weight 261.940
Density 2.0±0.1 g/cm3 Boiling Point 370.9±42.0 °C at 760 mmHg
Molecular Formula C5H10Br2O2 Melting Point N/A
MSDS USA Flash Point 178.1±27.9 °C

 Use of Glucose-6-phosphate dehydrogenase


Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is a major source of NADPH that is required by many essential cellular systems including the antioxidant pathways, nitric oxide synthase, NADPH oxidase, cytochrome p450 system, and others. Glucose-6-phosphate dehydrogenase can be used for the research of diabetes, aldosterone-induced endothelial dysfunction, and cancer[1].

 Names

Name Dehydrogenase glucose 6-phosphate
Synonym More Synonyms

 Glucose-6-phosphate dehydrogenase Biological Activity

Description Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is a major source of NADPH that is required by many essential cellular systems including the antioxidant pathways, nitric oxide synthase, NADPH oxidase, cytochrome p450 system, and others. Glucose-6-phosphate dehydrogenase can be used for the research of diabetes, aldosterone-induced endothelial dysfunction, and cancer[1].
Related Catalog

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 370.9±42.0 °C at 760 mmHg
Molecular Formula C5H10Br2O2
Molecular Weight 261.940
Flash Point 178.1±27.9 °C
Exact Mass 259.904755
LogP 0.38
Appearance of Characters suspension | white
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.574
Storage condition 2-8°C
Water Solubility Soluble in water and dilute buffer.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles112

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Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U. S. A. 105(31) , 10762-7, (2008)

The eukaryotic cell division cycle is characterized by a sequence of orderly and highly regulated events resulting in the duplication and separation of all cellular material into two newly formed daug...

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res. 14 , 2121-7, (2004)

The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for...

 Synonyms

Zwischenferment
EINECS 232-602-6
2,2-Bis(bromomethyl)-1,3-propanediol
6-Phosphoglucose dehydrogenase
2,2-Bis(bromomethyl)propane-1,3-diol
D-Glucose 6-phosphate dehydrogenase
Dehydrogenase
NADP-glucose-6-phosphate dehydrogenase
1,3-Propanediol, 2,2-bis(bromomethyl)-
MFCD00081656
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