Argininosuccinic acid disodium

Modify Date: 2024-01-02 15:30:12

Argininosuccinic acid disodium Structure
Argininosuccinic acid disodium structure
Common Name Argininosuccinic acid disodium
CAS Number 918149-29-8 Molecular Weight 354.26800
Density N/A Boiling Point N/A
Molecular Formula C10H20N4Na2O7 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Argininosuccinic acid disodium


Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].

 Names

Name Argininosuccinic acid disodium salt hydrate
Synonym More Synonyms

 Argininosuccinic acid disodium Biological Activity

Description Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].
Related Catalog
References

[1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244.  

[2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.  

 Chemical & Physical Properties

Molecular Formula C10H20N4Na2O7
Molecular Weight 354.26800
Exact Mass 354.11300
PSA 214.71000
Storage condition 20°C

 Synonyms

Argininosuccinic acid hydrate disodium salt