4,4'-Dihydroxybiphenyl

Modify Date: 2024-01-02 12:03:40

4,4'-Dihydroxybiphenyl Structure
4,4'-Dihydroxybiphenyl structure
Common Name 4,4'-Dihydroxybiphenyl
CAS Number 92-88-6 Molecular Weight 186.21
Density 1.2±0.1 g/cm3 Boiling Point 355.2±17.0 °C at 760 mmHg
Molecular Formula C12H10O2 Melting Point 280-282 °C(lit.)
MSDS Chinese USA Flash Point 176.1±15.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4,4'-Dihydroxybiphenyl


4,4'-Dihydroxybiphenyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name biphenyl-4,4'-diol
Synonym More Synonyms

 4,4'-Dihydroxybiphenyl Biological Activity

Description 4,4'-Dihydroxybiphenyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 4,4'-二羟基联苯用于制备塑料。用作实验室试剂和制备聚醚液晶的中间体。此外,它还用作橡胶和乳胶的抗氧化剂。除此之外,它还用于浅色橡胶制品、食品包装和医用乳胶制品。

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 355.2±17.0 °C at 760 mmHg
Melting Point 280-282 °C(lit.)
Molecular Formula C12H10O2
Molecular Weight 186.21
Flash Point 176.1±15.5 °C
Exact Mass 186.068085
PSA 40.46000
LogP 2.42
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.640
Water Solubility sparingly soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DV4725000
CHEMICAL NAME :
4,4'-Biphenyldiol
CAS REGISTRY NUMBER :
92-88-6
BEILSTEIN REFERENCE NO. :
1908886
LAST UPDATED :
199806
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H10-O2
MOLECULAR WEIGHT :
186.22
WISWESSER LINE NOTATION :
QR DR DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4920 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 208,61,1988

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H312-H315-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R21;R36/37/38
Safety Phrases S26-S36-S24/25-S36/37
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS DV4725000
HS Code 29061900

 Synthetic Route

 Customs

HS Code 2907299090
Summary 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

 Articles16

More Articles
Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists.

J. Med. Chem. 56(23) , 9664-72, (2013)

We show for the first time that bisphenol A (10) has the capacity to interact directly with K-Ras and that Rheb weakly binds to bisphenol A (10) and 4,4'-biphenol derivatives. We have characterized th...

Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp.

Mar. Biotechnol. 14(4) , 436-45, (2012)

Marine cyanobacteria are noted for their ability to excrete metabolites with biotic properties. This paper focuses on such exometabolites obtained from the culture of the marine filamentous cyanobacte...

Effects of the environmental oestrogens bisphenol A, tetrachlorobisphenol A, tetrabromobisphenol A, 4-hydroxybiphenyl and 4,4'-dihydroxybiphenyl on oestrogen receptor binding, cell proliferation and regulation of oestrogen sensitive proteins in the human breast cancer cell line MCF-7.

Pharmacol. Toxicol. 92(4) , 180-8, (2003)

Bisphenol A is extensively used in the manufacturing of epoxy resins and polycarbonate plastics, whereas several brominated and chlorinated analogues are used as flame retardants and intermediates in ...

 Synonyms

4,4'-Biphenyldiol
[1,1'-Biphenyl]-4,4'-diol
biphenyl-4,4'-diol
Antioxidant DOD
4,4'-Dioxydiphenyl
para,para'-Biphenol
EINECS 202-200-5
4,4'-Biphenol
4,4'-Diphenol
4,4'-dihydroxybiphenyl
4,4'-bis-hydroxybiphenyl
4,4`-Dihydroxybiphenyl
4-(4-hydroxyphenyl)phenol
DOD
4,4′-biphenol
p,p'-Diphenol
MFCD00002348
p,p'-Biphenol
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