trans-R-138727MP

Modify Date: 2024-01-09 21:33:59

trans-R-138727MP Structure
trans-R-138727MP structure
Common Name trans-R-138727MP
CAS Number 929211-64-3 Molecular Weight 497.57800
Density N/A Boiling Point N/A
Molecular Formula C27H28FNO5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of trans-R-138727MP


trans-R-138727MP (Prasugrel metabolite R-138727MP) is the active metabolite derivative of Prasugrel (HY-15284). Prasugrel, a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].

 Names

Name (2Z)-2-[1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-[2-(3-methoxyphenyl)-2-oxoethyl]sulfanylpiperidin-3-ylidene]acetic acid

 trans-R-138727MP Biological Activity

Description trans-R-138727MP (Prasugrel metabolite R-138727MP) is the active metabolite derivative of Prasugrel (HY-15284). Prasugrel, a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].
Related Catalog
References

[1]. Wijeyeratne YD, et al. Anti-platelet therapy: ADP receptor antagonists. Br J Clin Pharmacol. 2011 Oct;72(4):647-57.

 Chemical & Physical Properties

Molecular Formula C27H28FNO5S
Molecular Weight 497.57800
Exact Mass 497.16700
PSA 109.21000
LogP 4.49380
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