AZD 2066

Modify Date: 2024-01-23 21:11:31

AZD 2066 Structure
AZD 2066 structure
Common Name AZD 2066
CAS Number 934282-55-0 Molecular Weight 381.81600
Density N/A Boiling Point N/A
Molecular Formula C19H16ClN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AZD 2066


AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity[1].

 Names

Name 5-(3-chlorophenyl)-3-[(1R)-1-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)oxy]ethyl]-1,2-oxazole
Synonym More Synonyms

 AZD 2066 Biological Activity

Description AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity[1].
Related Catalog
References

[1]. Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350(2):212-22.

 Chemical & Physical Properties

Molecular Formula C19H16ClN5O2
Molecular Weight 381.81600
Exact Mass 381.09900
PSA 78.86000
LogP 4.32550
Storage condition 2-8°C

 Synonyms

unii-mq908y1zb2
azd2066
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