TPN729
Modify Date: 2024-01-02 23:38:35
TPN729 structure
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Common Name | TPN729 | ||
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| CAS Number | 936951-20-1 | Molecular Weight | 516.661 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H36N6O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TPN729TPN729 is a novel potent, selective phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 2.28 nM, shows better selectivity profile 2.5 times higher than sildenafil against PDE6 and 500 times higher than tadalafil against PDE11; selectively inhibits PDE5 and blocks the degradation of cyclic guanosine monophosphate, and is a promising PDE5 inhibitor providing fewer side effects and better compliance. |
| Name | TPN729 |
|---|
| Description | TPN729 is a novel potent, selective phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 2.28 nM, shows better selectivity profile 2.5 times higher than sildenafil against PDE6 and 500 times higher than tadalafil against PDE11; selectively inhibits PDE5 and blocks the degradation of cyclic guanosine monophosphate, and is a promising PDE5 inhibitor providing fewer side effects and better compliance. |
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| References | References 1. Wang Z, et al. J Sex Med. 2013 Nov;10(11):2790-7. 2. Zhu Y, et al. J Pharm Biomed Anal. 2016 Jan 5;117:217-26. View Related Products by Target Phosphodiesterase (PDE) |
| Molecular Formula | C25H36N6O4S |
|---|---|
| Molecular Weight | 516.661 |