N6,N6-dimethyladenine

Modify Date: 2024-01-04 00:17:33

N6,N6-dimethyladenine Structure
N6,N6-dimethyladenine structure
Common Name N6,N6-dimethyladenine
CAS Number 938-55-6 Molecular Weight 163.180
Density 1.4±0.1 g/cm3 Boiling Point 427.4±25.0 °C at 760 mmHg
Molecular Formula C7H9N5 Melting Point 259-262 °C(lit.)
MSDS Chinese USA Flash Point 212.3±23.2 °C

 Use of N6,N6-dimethyladenine


6-(Dimethylamino)purine is a dual inhibitor of protein kinase and CDK[1][2].

 Names

Name N6,N6-dimethyladenine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 427.4±25.0 °C at 760 mmHg
Melting Point 259-262 °C(lit.)
Molecular Formula C7H9N5
Molecular Weight 163.180
Flash Point 212.3±23.2 °C
Exact Mass 163.085800
PSA 57.70000
LogP 1.43
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.718
Storage condition −20°C
Water Solubility methanol: 0.1 g/mL, clear

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+: Very toxic;
Risk Phrases R25
Safety Phrases S26-S28-S36/37/39-S45-S24/25-S22
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS US9230000
Packaging Group II; III
HS Code 2933990090

 Synthetic Route

~95%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Agarwal, Anu; Chauhan, Prem M. S. Synthetic Communications, 2004 , vol. 34, # 16 p. 2925 - 2930

~82%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Holy, Antonin; Votruba, Ivan; Tloustova, Eva; Masojidkova, Milena Collection of Czechoslovak Chemical Communications, 2001 , vol. 66, # 10 p. 1545 - 1592

~57%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Motawia; Meldal; Sofan; Stein; Pedersen; Nielsen Synthesis, 1995 , # 3 p. 265 - 270

~94%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Itaya, Taisuke; Matsumoto, Hiroo; Ogawa, Kazuo Chemical & Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1920 - 1924

~74%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Alves, M. Jose; Carvalho, M. Alice; Carvalho, Silvia; Dias, Alice M.; Fernandes, Francisco H.; Proenca, M. Fernanda European Journal of Organic Chemistry, 2007 , # 29 p. 4881 - 4887

~74%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Alves, M. Jose; Carvalho, M. Alice; Carvalho, Silvia; Dias, Alice M.; Fernandes, Francisco H.; Proenca, M. Fernanda European Journal of Organic Chemistry, 2007 , # 29 p. 4881 - 4887

~%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Journal of Heterocyclic Chemistry, , vol. 20, p. 295 - 299

~%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Tetrahedron, , vol. 43, # 6 p. 1133 - 1140

~%

N6,N6-dimethyladenine Structure

N6,N6-dimethyla...

CAS#:938-55-6

Literature: Tetrahedron, , vol. 43, # 6 p. 1133 - 1140

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Proc. Natl. Acad. Sci. U. S. A. 104 , 20523-8, (2007)

Protein kinases play a pivotal role in cell signaling, and dysregulation of many kinases has been linked to disease development. A large number of kinase inhibitors are therefore currently under inves...

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 Synonyms

UNII:649SA4S2CV
7H-Purin-6-amine, N,N-dimethyl-
N,N-dimethyl-7H-purin-6-amine
N(6),N(6)-dimethyladenine
N,N-Dimethyl-1H-purin-6-amine
N,N-Dimethyl-6-aminopurine
EINECS 214-353-5
N6,N6-dimethyl-Adenine
1H-purin-6-amine, N,N-dimethyl-
Adenine, N6,N6-dimethyl-
6-(dimethylamino)-Purine
MFCD00005573
Dimethylaminopurine
6-Dimethylaminopurine
N,N-dimethyl-adenine
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