p,p'-DDD-d8

Modify Date: 2024-01-05 15:10:16

p,p'-DDD-d8 structure	Common Name	p,p'-DDD-d8
	CAS Number	93952-20-6	Molecular Weight	328.09000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₂Cl₄D₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of p,p'-DDD-d8

p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD is a major metabolite of p,p'-DDT. p,p'-DDD occurs in the feces and livers of rats, that are given p,p'-DDT by stomach tube, but not of rats injected intraperitoneally with p,p'-DDT[2][3].

Name	4,4′-Dichlorobenzophenone D8

Description	p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD is a major metabolite of p,p'-DDT. p,p'-DDD occurs in the feces and livers of rats, that are given p,p'-DDT by stomach tube, but not of rats injected intraperitoneally with p,p'-DDT[2][3].
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Mendel JL, et al. Conversion of p,p' -DDT to p,p' -DDD by intestinal flora of the rat. Science. 1966;151(3717):1527-1528. [3]. Gerić M, et al. Cytogenetic status of human lymphocytes after exposure to low concentrations of p,p'-DDT, and its metabolites (p,p'-DDE, and p,p'-DDD) in vitro. Chemosphere. 201287(11):1288-1294.

Molecular Formula	C₁₄H₂Cl₄D₈
Molecular Weight	328.09000
Exact Mass	326.00400
LogP	5.92900

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4,4′-DICHLOROBENZOPHENONE D8
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

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p,p'-DDD-d8

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p,p'-DDD-d8 Biological Activity

Chemical & Physical Properties