TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE

Modify Date: 2024-01-23 02:04:21

TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE Structure
TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE structure
Common Name TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE
CAS Number 942145-27-9 Molecular Weight 272.38400
Density 1.026g/cm3 Boiling Point 370.2ºC at 760 mmHg
Molecular Formula C14H28N2O3 Melting Point N/A
MSDS N/A Flash Point 177.7ºC

 Names

Name tert-butyl N-[(2S)-1-amino-3-[(3R)-oxan-3-yl]propan-2-yl]-N-methylcarbamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.026g/cm3
Boiling Point 370.2ºC at 760 mmHg
Molecular Formula C14H28N2O3
Molecular Weight 272.38400
Flash Point 177.7ºC
Exact Mass 272.21000
PSA 64.79000
LogP 2.69760
Index of Refraction 1.479
Storage condition 2-8°C

 Safety Information

HS Code 2932999099

 Synthetic Route

~92%

TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE Structure

TERT-BUTYL ((S)...

CAS#:942145-27-9

Literature: VITAE PHARMACEUTICALS, INC. Patent: WO2008/156817 A2, 2008 ; Location in patent: Page/Page column 94; 99 ; WO 2008/156817 A2

~93%

TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE Structure

TERT-BUTYL ((S)...

CAS#:942145-27-9

Literature: Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

~98%

TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE Structure

TERT-BUTYL ((S)...

CAS#:942145-27-9

Literature: VITAE PHARMACEUTICALS, INC. Patent: WO2009/154766 A1, 2009 ; Location in patent: Page/Page column 47 ; WO 2009/154766 A1

~%

TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE Structure

TERT-BUTYL ((S)...

CAS#:942145-27-9

Literature: Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

~%

TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE Structure

TERT-BUTYL ((S)...

CAS#:942145-27-9

Literature: Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

~%

TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE Structure

TERT-BUTYL ((S)...

CAS#:942145-27-9

Literature: Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

CarbaMic acid,N-[(1S)-1-(aMinoMethyl)-2-[(3R)-tetrahydro-2H-pyran-3-yl]ethyl]-N-Methyl-,1,1-diMethylethyl ester
QC-4591
tert-butyl ((S)-1-aminomethyl-2-(R)-tetrahydro-pyran-3-yl-ethyl)-methyl-carbamate
1,1-dimethylethyl {(1S)-2-amino-1-[(3R)-tetrahydro-2H-pyran-3-ylmethyl]ethyl}methylcarbamate
tert-Butyl ((S)-1-amino-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl)(methyl)carbamate